The Pathophysiology, Diagnostic Approach and Therapeutic Management of Ischemic Heart Disease: From Simple to Complex

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 15 July 2024 | Viewed by 366

Special Issue Editors


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Guest Editor
Department of Internal Medicine I (Cardiology), Faculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, Romania
Interests: acute heart failure; biomarker analysis; cardiomyopathies; acute myocardial infarction; interventional cardiology

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Guest Editor
Department of Morpho-Functional Sciences (II), Faculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, Romania
Interests: myocardial ischemia; oxidative stress; apoptosis; cardiac biomarkers

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Guest Editor
Department of Internal Medicine I (Cardiology), Faculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, Romania
Interests: heart failure

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Guest Editor
Department of Internal Medicine I (Cardiology), Faculty of Medicine, University of Medicine and Pharmacy “Grigore T Popa”, 700115 Iasi, Romania
Interests: chronic heart failure; cardiac biomarkers; ischemic heart disease
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Special Issue Information

Dear Colleagues,

Despite continuous progress in its screening and therapeutic approaches, coronary artery disease (CAD) still emerges as the leading cause for the development and progression of heart failure (HF). The classic integrative strategy of these pathologies focuses on the use of multiple diagnostic tools: clinical, imaging, and biological, followed by both pharmacological and invasive guideline-directed therapeutic management.

Additionally, the complex interplay between CAD and HF is also mirrored by the increasing number of patients presenting with myocardial ischemia and necrosis, but without angiographically significant coronary lesions. In these patients, the pathogenesis as well as the diagnostic and therapeutic approaches are different from CAD with obstructive coronary arteries; therefore, the use of novel techniques (intracoronary imaging, invasive hemodynamic assessment, or cardiac multimodality imaging) is of paramount importance for a timely diagnosis and targeted treatment. Therefore, in this Special Issue, we aim to depict various pathophysiological, clinical, biological, and therapeutical aspects of both obstructive CAD and myocardial infarction with nonobstructive coronary arteries (MINOCA).

A topic of particular interest in this Special Issue is represented by cardiac biomarkers as an integral part of the diagnostic algorithm in CAD. Various classic or novel molecules may provide an objective insight into the pathophysiological imbalances induced by myocardial ischemia, devoid of the subjectivity of patient symptoms, or the often equivocal and operator-dependent imaging aspects.

We aim to update the information on the challenging approach for patients with HF due to CAD; therefore, we welcome all submissions (original research articles or reviews) related to this topic, with a special focus on novel or innovative diagnostic or therapeutic instruments.

Dr. Radu-Stefan Miftode
Prof. Dr. Ionela Lacramioara Serban
Prof. Dr. Antoniu Octavian Petris
Prof. Dr. Irina Iuliana Costache
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ischemic heart disease
  • acute heart failure
  • cardiac biomarkers
  • antithrombotic therapy
  • percutaneous coronary intervention

Published Papers

This special issue is now open for submission.
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