Antifungal Natural Substances and Actives

Dear Colleagues,

In recent years, the extensive abuse of chemicals to control diseases has been associated with the increasing number of multidrug-resistant pathogens. The growth of fungi resistant to conventional antimicrobial agents is one of the biggest concerns worldwide. The problem of fungal infections in humans, veterinary, and environmental settings is constantly growing. Pathogenic fungi, such as human cells, are eukaryotic, and potential selective drugs can only attack limited targets. However, the only licensed antifungal therapies, polyenes, azoles, echinocandins, and flucytosine, suffer several limitations due to cross-target toxicity. Thus, the need for more effective and less toxic antifungal agents is mandatory. In this scenario, the search for new alternative natural resources, alone or in combination with conventional molecules, is desirable both to bypass the new resistances and to define effective therapeutic approaches with fewer side effects. Essential oils are among the most promising natural substances due to their marked antifungal characteristics. These natural substances are complex mixtures of volatile active components obtained from aromatic plants through distillation or pressing processes. This Special Issue welcomes the submission of scientific articles on the topic of "Antifungal Natural Substances and Actives". Original articles, brief reports, case reports, reviews, and mini reviews that analyse the antifungal efficacy of essential oils and their components, both against filamentous fungi and yeasts, according to a “one health approach”, will be accepted.

Dr. Maura Di Vito
Dr. Francesca Bugli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Candida spp
• dermatophytes
• fungal resistance
• synergy with antifungal drugs
• GC-MS analysis