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J. Compos. Sci.
Special Issues
Nanocomposites for Biomedical and Environmental Applications
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Nanocomposites for Biomedical and Environmental Applications

A special issue of Journal of Composites Science (ISSN 2504-477X). This special issue belongs to the section "Nanocomposites".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 4325

Special Issue Editor

Prof. Dr. Huirong Le

E-Mail Website
Guest Editor
The Future Lab, Tsinghua University, Beijing, China
Interests: biomaterials; surface coatings; composite materials; mechanical behaviour of materials

Special Issue Information

Dear Colleagues,

The development of nanomaterials such as nanoparticles, nanotubes, and nanoplatelets has inspired more and more nanocomposites with polymeric, metallic or ceramic matrices. The addition of nanomaterials may give the matrix material new characteristics and new functions. One potential field of application is medical implants and tissue engineering, such as dental implant, hip/knee joint, bone cement, bone graft, implantable monitoring/drug delivery devices or scaffolds for tissue engineering. Ceramic nanoparticles or nanotubes are often used as reinforcement and a bioactive agent in polymeric or cement nanocomposites. Nanocomposite materials can be used as a coating material as well as bulk material. Metallic implants usually lack compatibility with live tissues, which can be improved with a nanocomposite coating for antibacterial property and biocompatibility. More applications are emerging in other industries, where there is a strong demand for anti-fouling and photocatalytic materials to protect against microbial buildup and toxic organic substances.

There are a few points that still need to be addressed before these new materials can be applied by practitioners, which include production and standardization of nanomaterials, achievement of good dispersions in matrices, processing of nanocomposites to achieve desirable mechanical properties, and interaction with the biological/living environment. Extensive investigation is being done to address these issues to take nanocomposite materials into industrial applications.

The aim of the contributions to this volume will be to report advances in the design and processing of nanocomposite materials, our understanding of the interface of nanomaterials with different types of matrices, and how these composite materials interact with microbes or toxic organic matter in the environment. Advances in the development of nanocomposite scaffolds for tissue engineering (such as ligament, tendons, etc.) and research on nanocomposite architecture and biointeractions with great potential to open the door to clinical or industrial applications are particularly encouraged in this Special Issue. Both original articles and topical reviews are welcome.

Prof. Dr. Huirong Le
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Composites Science is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nanocomposites
  • Surface coatings
  • Medical implants
  • Tissue engineering
  • Antimicrobial materials
  • Water treatment

Published Papers (2 papers)

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Research

12 pages, 3222 KiB  
Article
Green Synthesis of Selenium Nanoparticles Using Cleistocalyx operculatus Leaf Extract and Their Acute Oral Toxicity Study
by Tri Thien Vu, Phuong Thi Mai Nguyen, Ngan Hanh Pham, Thanh Huu Le, Tran Hung Nguyen, Dinh Trung Do and Duong Duc La
J. Compos. Sci. 2022, 6(10), 307; https://doi.org/10.3390/jcs6100307 - 12 Oct 2022
Cited by 9 | Viewed by 2539
Abstract
Green synthesis has recently attracted extensive attention from scientists all over the world for the production of metal nanoparticles. Selenium nanoparticles (Se NPs) have been demonstrated as a suitable supplement nutrient for the replacement of selenium ions in terms of safety and efficiency. [...] Read more.
Green synthesis has recently attracted extensive attention from scientists all over the world for the production of metal nanoparticles. Selenium nanoparticles (Se NPs) have been demonstrated as a suitable supplement nutrient for the replacement of selenium ions in terms of safety and efficiency. This work presented a friendly and facile approach to synthesize the Se NPs using polyphenols content in the Cleistocalyx operculatus (CO) leaves extract. The synthesizing conditions were optimized to obtain the Se NPs with uniform distribution and shape. The prepared Se NPs were well-characterized using scanning electron microscopy, X-ray diffraction, energy diffractive spectroscopy, and Fourier-transform infrared spectroscopy. The resultant Se NPs were in spherical shape with the particle size in a range from 50–200 nm. The antimicrobial properties of Se NPs were investigated against Echerichia coli and Staphylococcus aureus, which showed reasonable activity. The acute oral toxicity of Se NPs in mice was also studied. The result indicated that Se NPs exhibited lower toxicity than that of SeO2 with the lethal concentration (50% death of mice) of 7.75 mg kg−1. Full article
(This article belongs to the Special Issue Nanocomposites for Biomedical and Environmental Applications)
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8 pages, 1767 KiB  
Article
Synthesis of Vectorized Nanoparticles Based on a Copolymer of N-Vinyl-2-Pyrrolidone with Allyl Glycidyl Ether and a Carbohydrate Vector
by Dmitry Z. Vinnitskiy, Anna L. Luss, Vadim B. Krylov, Nadezhda E. Ustyuzhanina, Anastasiya V. Goryachaya, Anna M. Nechaeva, Mikhail I. Shtilman, Nikolay E. Nifantiev and Yaroslav O. Mezhuev
J. Compos. Sci. 2022, 6(9), 247; https://doi.org/10.3390/jcs6090247 - 25 Aug 2022
Viewed by 1394
Abstract
A method was developed for the conjugation of aminopropyl spacer-bearing carbohydrates with epoxy groups on the crown of nanoparticles consisting of a copolymer of N-vinyl-2-pyrrolidone and allyl glycidyl ether in basic buffer, opening prospects for the design of vectorized nanocomposite drug forms. A [...] Read more.
A method was developed for the conjugation of aminopropyl spacer-bearing carbohydrates with epoxy groups on the crown of nanoparticles consisting of a copolymer of N-vinyl-2-pyrrolidone and allyl glycidyl ether in basic buffer, opening prospects for the design of vectorized nanocomposite drug forms. A conjugate of the above copolymer and trisaccharide A, a synthetic blood group antigen, was synthesized. Meglumine was used to bind any unreacted epoxide groups of the allyl glycidyl fragment. One- and two-dimensional NMR spectroscopy showed quantitative opening of the epoxide ring as a result of carbohydrate immobilization. By integrating the characteristic signals in the 1H NMR spectrum, we determined the molar ratio of the immobilized vector and meglumine, as well as the composition and number-average molecular weight of the carrier copolymer. The results obtained point to the interesting possibilities in the further study of the polymer–carbohydrate ligand system as a platform for the development of several drug carriers and theranostics based on them. Full article
(This article belongs to the Special Issue Nanocomposites for Biomedical and Environmental Applications)
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