Special Issue "Advances in Metal Metabolism Research 2.0"
Deadline for manuscript submissions: 1 October 2023 | Viewed by 2085
Interests: environmental toxicology and ecotoxicology; molecular physiology; microevolution of metal sensitivity; evolution; biochemistry and gene regulation of metallothioneins; metal-specific pathways in animal physiology; metal detoxification; metal-related biological indicators and biomarkers
Special Issues, Collections and Topics in MDPI journals
After the publication of two issues in the International Journal of Molecular Sciences dedicated to “Metal Metabolism in Animals” (in 2016 and 2017), one may ask about the reasonableness of adding a third issue to this series. In fact, the subject of metal metabolism in animals in this journal has so far been treated in a very thorough manner. In the first issue (“Metal Metabolism in Animals I”, edited 2016), articles were dedicated to subjects like the significance of metals, metal-binding features and the role of metals in metalloproteins, metal homeostasis and detoxification, as well as trace element supplementation in animals. In the second issue (“Metal Metabolism in Animals II”, edited 2017), the perspective was extended to human beings with articles focusing on aspects of metal allergy and immunology, models of metal uptake and effects during pregnancy, as well as toxicological and pathological effects of metals on animals and humans.
During the last years, an increasing number of publications has appeared dealing with the molecular evolutionary aspects of metal handling in organisms. Thus, it was shown that in addition to traditional aspects of metallomics, evolutionary approaches could help one to better understand how strategies of metal handling have gradually been shaped through generations and lineages of organisms from all domains of life, and how this may have fostered adaptation to their different environments. This has undoubtedly increased our perception of these processes of adaptation. An evolutionary view may also increase our understanding of how ancestral metal handling features may have been optimized towards more complex and, perhaps, more efficient mechanisms and interconnections.
Although articles dealing with molecular evolutionary aspects of metal metabolism were not explicitly excluded in the former issues, we would like on this occasion to put a particular focus on these subjects, including now living organisms across all domains of life.
Thus, in particular, we welcome articles with a strong molecular and metallomic focus, dealing with the following topics:
- The molecular evolutionary aspects of mechanisms and strategies of trace-element uptake, regulation, and homeostasis in all kinds or organisms;
- The evolution of metal-binding proteins and metallo-enzymes, and their interaction with other cellular components through time and across lineages and populations;
- The evolution of metal regulatory gene-networks;
- The evolutionary, micro-evolutionary, and population-specific effects of metal handling in all species of organisms, both under laboratory conditions and in the wild;
- The epigenetic aspects and mechanisms of metal-handling strategies;
- The effects of metal toxicity under an epigenetic perspective;
- Evolutionary engineering and optimization in the laboratory or in the field of metal-handling proteins and of genes involved in metal metabolism;
- Any other topic focusing, in an integrative manner, on the evolution and phylogeny of metal-handling mechanisms and metal metabolism in all kinds of organisms.
Prof. Dr. Reinhard Dallinger
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- molecular evolution
- gene networks
- metal metabolism
- metal toxicity
- metal homeostasis
- metallo-enzymes and metallo-proteins
- evolutionary engineering