New Insights in Biomarkers of Autoimmune and Autoinflammatory Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 30 August 2024 | Viewed by 611
Special Issue Editors
2. Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, Italy
Interests: immunology; autoimmunity; inflammation; biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: autoimmunity; cancer; monoclonal gammopathy; minimal residual disease; biomarkers; other biological fluid; new technologies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The deregulation of innate and adaptive immune systems affects 5% of the worldwide population with a high impact in terms of clinical impairment, morbidity, and, due to the chronic conditions, a significant economic burden in the long run. Inflammation, the long arm of innate immunity, as a mediator of effects may be involved or deregulated in itself, in absence of an auto-attack of the immune system, paving the way for those conditions included under the umbrella name of autoinflammatory diseases. Accordingly, cellular and molecular biomarkers are largely involved in diagnosis, prognosis, response to therapies, and follow-up, providing a prediction of changes in disease activity. Taking into account the individual and genetic susceptibility as well as the wide range of environment risk factors that concur with the pathogenesis, the importance of research to set-up and validate novel, effective, and personalised biomarkers of autoimmune and autoinflammatory conditions stands alone. This Special Issue is devoted to the most recent results aimed at exploiting the clinical potential of biomarkers measuring the disordered immune response.
Potential topics include, but are not limited to:
- Innate immunity;
- Adaptive immunity;
- Inflammation;
- Immunoglobulins;
- Autoantibodies;
- Free light chains;
- Peptides;
- Cytokines;
- Receptors;
- Leukocytes;
- Extracellular vesicles;
- Signal transduction;
- Inflammaging;
- Inflammasome.
Dr. Mariapaola Marino
Dr. Umberto Basile
Guest Editors
Manuscript Submission Information
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Keywords
- inflammaging
- inflammasome
- autoantibodies
- free light chains
- cytokines
- receptor
- signal transduction
- innate immunity
- adaptive immunity
