Special Issue "New Advances in Inflammasomes"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 December 2023 | Viewed by 582
Special Issue Editors
2. Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, Italy
Interests: immunity; pathology; myasthenia gravis
Interests: autoimmunity; cancer; monoclonal gammopathy; minimal residual disease; biomarkers; other biological fluid; new technologies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The increased morbidity and mortality due to the coronavirus disease 2019 in subjects with chronic conditions and a compromised immune system result from the host–coronavirus interaction, and inflammasomes have been proposed as important players. The activation of inflammasomes, which are multimeric protein complexes, is a crucial component of the innate immune response and is essential for the elimination of pathogens or damaged cells through the secretion of IL-1β and IL-18 and the induction of pyroptosis. However, the dysregulated activation of inflammasomes is involved in the pathogenesis of different autoimmune–autoinflammatory, neurodegenerative, and metabolic disorders that share the common line of inflammation in their pathogenetic fingerprint. Inhibition of inflammasome activation shows therapeutic effects and a wide range of anti-inflammatory compounds are currently being employed. This Special Issue is devoted to the most recent advances in the biology of inflammasomes and their engagement in human diseases.
Potential topics include, but are not limited to:
- Inflammation;
- Autoinflammatory diseases;
- Cardiovascular diseases;
- Neurodegenerative disorders;
- Metabolism;
- Infections;
- Mechanisms of action;
- Molecular targeting therapy.
Dr. Mariapaola Marino
Dr. Umberto Basile
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- clinical perspectives
- pyroptosis
- nod like receptor protein 3
- inflammatory diseases
- cytokines
- inflammasome
- biomarkers of inflammasome activation
