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Novel Biomaterials for Dental Applications and Antimicrobial Applications
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Novel Biomaterials for Dental Applications and Antimicrobial Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: closed (15 April 2024) | Viewed by 2134

Special Issue Editor

Dr. Simona Liliana Iconaru

E-Mail Website
Guest Editor
National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
Interests: biomaterials; biomedical applications; environmental applications; surface analysis; antimicrobial properties
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, nanotechnology has seen tremendous progress in the field of biomedical applications. Despite this important progress, the World Health Organization has emphasized that in almost all developed countries, dental caries represent a serious health problem, and more than two-thirds of the global population has a form a tooth decay; this often results in cavities, leading to the appearance of lesions of varying degrees of severity. In this context, the main focus of the scientific community has been aimed at the development of novel materials with enhanced stable and controllable physico-chemical parameters and enhanced biological activity. Moreover, recently, with one of the most pressing problems worldwide being the emergence of drug-resistant microorganisms responsible for the appearance of life-changing conditions in dentistry, special attention has been paid to biomaterials that exhibit antimicrobial properties. This Special Issue welcomes both original articles and reviews dedicated to the development and characterization of novel biomaterials with enhanced antimicrobial properties, which could be used in both biomedical as well as dentistry applications.

Dr. Simona Liliana Iconaru
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • biomedical applications
  • dentistry
  • antimicrobial properties

Published Papers (1 paper)

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Review

14 pages, 3184 KiB  
Review
Effect of Chitosan on the Number of Streptococcus mutans in Saliva: A Meta-Analysis and Systematic Review
by Virág Róna, Bulcsú Bencze, Kata Kelemen, Dániel Végh, Réka Tóth, Tamás Kói, Péter Hegyi, Gábor Varga, Noémi Katinka Rózsa and Zoltán Géczi
Int. J. Mol. Sci. 2023, 24(20), 15270; https://doi.org/10.3390/ijms242015270 - 17 Oct 2023
Cited by 1 | Viewed by 1775
Abstract
We conducted a meta-analysis and systematic review to investigate the efficacy of chitosan-containing chewing gums, and to test their inhibitory effects on Streptococcus mutans. The systematic search was performed in three databases (Cochrane Library, EMBASE, and PubMed) and included English-language randomized–controlled trials [...] Read more.
We conducted a meta-analysis and systematic review to investigate the efficacy of chitosan-containing chewing gums, and to test their inhibitory effects on Streptococcus mutans. The systematic search was performed in three databases (Cochrane Library, EMBASE, and PubMed) and included English-language randomized–controlled trials to compare the efficacy of chitosan in reducing the number of S. mutans. To assess the certainty of evidence, the GRADE tool was used. Mean differences were calculated with a 95% confidence interval for one outcome: bacterial counts in CFU/mL. The protocol of the study was registered on PROSPERO, registration number CRD42022365006. Articles were downloaded (n = 6758) from EMBASE (n = 2255), PubMed (n = 1516), and Cochrane (n = 2987). After the selection process, a total of four articles were included in the qualitative synthesis and three in the quantitative synthesis. Our results show that chitosan reduced the number of bacteria. The difference in mean quantity was −4.68 × 105. The interval of the random-effects model was [−2.15 × 106; 1.21 × 106] and the prediction interval was [1.03 × 107; 9.40 × 106]. The I2 value was 98% (p = 0.35), which indicates a high degree of heterogeneity. Chitosan has some antibacterial effects when used as a component of chewing gum, but further studies are needed. It can be a promising antimicrobial agent for prevention. Full article
(This article belongs to the Special Issue Novel Biomaterials for Dental Applications and Antimicrobial Applications)
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