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Theoretical Approaches in Molecular Sciences

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 864

Special Issue Editor

Special Issue Information

Dear Colleagues,

Many theoretical tools from various origins (mathematics, computer science, statistics, theoretical physics, etc.) are used to model the structure and dynamics of molecules, especially in biology. The general theme of this Special Issue is broad and can correspond to the following topics:

  • Enzymatic kinetics;
  • Membrane dynamics;
  • Molecular aspects of the genetic networks;
  • Molecular aspects of the metabolic networks;
  • Protein/RNA interactions;
  • Phylogenies of biological molecules;
  • Chemistry of the origin of life;
  • Molecular modeling in immunology;
  • Molecular modeling in epigenetics;
  • Molecular modeling of the cell respiration;
  • Molecular models of the biological rhythms;
  • Molecular models of the embryonic development;
  • Molecular interactions in brain functioning.

Prof. Dr. Jacques Demongeot
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

17 pages, 9730 KiB  
Article
An Unsupervised Classifier for Whole-Genome Phylogenies, the Maxwell© Tool
by Joël Gardes, Christophe Maldivi, Denis Boisset, Timothée Aubourg and Jacques Demongeot
Int. J. Mol. Sci. 2023, 24(22), 16278; https://doi.org/10.3390/ijms242216278 - 13 Nov 2023
Viewed by 655
Abstract
The development of phylogenetic trees based on RNA or DNA sequences generally requires a precise and limited choice of important RNAs, e.g., messenger RNAs of essential proteins or ribosomal RNAs (like 16S), but rarely complete genomes, making it possible to explain evolution and [...] Read more.
The development of phylogenetic trees based on RNA or DNA sequences generally requires a precise and limited choice of important RNAs, e.g., messenger RNAs of essential proteins or ribosomal RNAs (like 16S), but rarely complete genomes, making it possible to explain evolution and speciation. In this article, we propose revisiting a classic phylogeny of archaea from only the information on the succession of nucleotides of their entire genome. For this purpose, we use a new tool, the unsupervised classifier Maxwell, whose principle lies in the Burrows–Wheeler compression transform, and we show its efficiency in clustering whole archaeal genomes. Full article
(This article belongs to the Special Issue Theoretical Approaches in Molecular Sciences)
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