Special Issue "Viral Nuclear Transport: From Molecular Pathogenesis to Antiviral Therapy"
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 4625
Interests: nucleo-cytoplasmic shuttling; protein–protein interactions; antiviral drug discovery; viral replication
Special Issues, Collections and Topics in MDPI journals
Viruses intensively interact with the host cell nucleocytoplasmic nuclear transport apparatus at different levels. Indeed, viral proteins can be actively translocated across the nuclear pore complex or interfere with the cellular nucleocytoplasmic transport process itself. These events are crucial for viral genome nuclear targeting, expression, replication, and encapsidation, as well as for host cell function manipulation, with profound effects on cell proliferation, survival, and antiviral response. Furthermore, recent developments of broad and specific nuclear transport inhibitors suggest a potential future pharmacological implication for antiviral drug discovery.
This Special Issue will welcome original research and review articles dealing with functional, biochemical, and structural aspects on the subject, including the following topics:
- Nucleocytoplasmic trafficking of viral proteins;
- Interaction of viral proteins with cellular transporters;
- Nuclear delivery and egress of viral genomes;
- Modulation of the nuclear pore function and composition during viral infection;
- Delocalization of nucleoporins to viral replication factories;
- Antiviral implications of nucleocytoplasmic transport inhibitors.
Dr. Gualtiero Alvisi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.