Special Issue "Antioxidants in Male Human and Animal Reproduction: In Vitro and In Vivo Studies"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 8239
Interests: male infertility; sperm quality; sperm morphology; microscopies
Interests: isoprostanes; neuroprostanes; markers of oxidative stress; oxidative stress in human diseases
Special Issues, Collections and Topics in MDPI journals
Oxidative stress (OS) affects the quality of gametes and plays a central role in the pathogenesis of male infertility. OS is exacerbated during laboratory procedures for semen handling, such as centrifugation and cryopreservation, as well as during the protocols for assisted fertilization technologies, both in human and animal species. Treatment strategies for OS include the use of both synthetic and natural antioxidants administered in vivo and used in vitro, for example, cell supplement in culture and cryopreservation media. In the last few years, various interesting bioactive factors, such as ghrelin, obestatin, melatonin, and some adipocytokines, have demonstrated a protective antioxidant effect worthy of investigation in the field of animal and human reproduction. Studies on the effects of diets supplemented with different antioxidant molecules in animal models may represent a starting point for managing male infertility.
- In vitro studies of antioxidants in human and animal sperm;
- Relevance of antioxidants in semen cryopreservation and semen handling;
- Antioxidants and spermatogenesis;
- Antioxidant effect on human male infertility—mechanisms, molecular signaling, sperm quality;
- Molecular effects of antioxidants on male reproduction—investigations in animal models;
- Relevance of constitutive antioxidants in male infertility and animal models;
- Antioxidant-based diet in animal model of male infertility.
Dr. Elena Moretti
Dr. Cinzia Signorini
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- animal models
- antioxidant signaling
- male infertility
- natural antioxidants
- oxidative stress
- synthetic antioxidants