Potential Health Benefits of Dietary Antioxidants

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 1177

Special Issue Editor

Special Issue Information

Dear Colleagues,

Dietary antioxidants are a widespread family of molecules characterized by their chemical structure (e.g., phenols, vitamins, peptides, etc.), chemical–physical properties (e.g., lipophilic or hydrophilic), and activity (enzymatic or nonenzymatic). They mitigate oxidative stress due to excessive and uncontrolled reactive oxygen species (ROS; i.e., singlet oxygen, peroxynitrite, hydroxyl radical OH, superoxide ion O2, hydrogen peroxide H2O2) and free radical production. Exogenous (i.e., smoke, pollutants, and radiation) and endogenous factors (i.e., aerobic metabolism in mitochondria, enzymatic reactions, etc.) induce their production. Oxidative stress causes inflammation, cardiovascular diseases, neurodegenerative illnesses, asthma, senescence, cancer, and premature skin aging. Food's antioxidative capacity is determined by a range of compounds, some of which may not be identified after their metabolization. Depending on their concentration, specific antioxidants may lead to under- or overestimating antioxidant activity since they work synergistically. In recent years, the consumption of functional foods and food supplements containing food antioxidants has expanded exponentially. Recently, supplements based on single antioxidants and extracts containing food antioxidants have been formulated. Unfortunately, many antioxidants act as prooxidants at high concentrations, increasing to oxidative stress and inducing toxicity. This Special Issue aims to collect reviews and research articles in which dietary antioxidants' isolation, characterization, uses, delivery systems and toxicological aspects are reported. 

Dr. Irene Dini
Guest Editor

Manuscript Submission Information

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Keywords

  • food antioxidants
  • food supplements
  • antioxidant activity
  • food antioxidant isolation
  • food antioxidant characterization
  • analytical method validation
  • antioxidant bioavailability
  • circular economy
  • sustainability

Published Papers (1 paper)

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Research

16 pages, 530 KiB  
Article
Dietary Antioxidants May Support Cosmetic Treatment in Patients with Rosacea
by Kinga Zujko-Kowalska, Joanna Masłowska, Małgorzata Knaś-Dawidziuk, Jadwiga Hamulka and Małgorzata Elżbieta Zujko
Antioxidants 2024, 13(3), 381; https://doi.org/10.3390/antiox13030381 - 21 Mar 2024
Viewed by 899
Abstract
Rosacea is a chronic skin disease that significantly reduces the quality of life (QoL) of patients. The aim of this study was to assess whether dietary antioxidants can support the effect of cosmetic treatment in improving the QoL of patients with rosacea. Basic [...] Read more.
Rosacea is a chronic skin disease that significantly reduces the quality of life (QoL) of patients. The aim of this study was to assess whether dietary antioxidants can support the effect of cosmetic treatment in improving the QoL of patients with rosacea. Basic data about participants (N = 160) were collected using a self-reported survey. QoL was assessed using the standardized Dermatology Life Quality Index (DLQI) questionnaire. An interventional cosmetic treatment was performed using cavitation peeling and sonophoresis with a commercial capillary repair serum. The study was registered as a clinical trial (NCT06271135). To assess antioxidant diet quality, for the first time, a new dietary antioxidant quality index (DAQI) was developed, which consisted of 12 items: dietary total antioxidant capacity, dietary polyphenols, phytosterols, lignans, vitamin C, vitamin E, β-carotene, zinc, iron, copper, manganese and selenium. It was found that the highest tertiles of DAQI diminished the odds about 40–45% of the moderate, large and extremely large effect of rosacea on QoL and about 8–11% of the occurrence of rosacea symptoms compared with the lowest tertile. This study showed that rosacea has a negative impact on QoL, but a comprehensive approach to treatment, including antioxidant cosmetic treatment and dietary antioxidants, can improve the QoL of patients with rosacea. Full article
(This article belongs to the Special Issue Potential Health Benefits of Dietary Antioxidants)
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