VOC Metabolites from Environment to Health

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Environmental Metabolomics".

Deadline for manuscript submissions: closed (15 January 2024) | Viewed by 1356

Special Issue Editors


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Laboratory for Instrumentation, Biomedical Engineering and Radiation Physics (LIBPhys - UNL), Department of Physics, NOVA School of Science and Technology, NOVA University of Lisbon, Campus FCT-UNL, 2829-516 Caparica, Portugal
Interests: sensors; ion mobility spectrometry; VOCs; environmental health; VOC biomarkers; toxicology; metabolites; breath analysis

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Applied Molecular Biosciences Unit (UCIBIO), Department of Chemistry, NOVA School of Science and Technology, NOVA University of Lisbon, 2829-516 Caparica, Portugal
Interests: environmental toxicology; oxidative stress; proteomics; climate change; food safety
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CESAM—Centre for Environmental and Marine Studies, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal
Interests: atmospheric organic aerosols; water-soluble organic aerosols; source signatures; health effects of organic aerosols; wet and dry deposition of organic aerosols; atmospheric stressors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Volatile organic compounds (VOCs) are generally associated with odours from compounds produced by living organisms or pollutants, and are also used as markers for some diseases. Both VOCs and certain metabolites are of great relevance in biological processes, playing very important roles in the communication between animals and plants, and have a key role in the reproduction process of some species. From more traditional analytical techniques (e.g. GC-MS) to more innovative techniques (e.g. GC-IMS) to sample processing methods, there have been many advancements. On the other hand, VOC analysis is very important for environmental condition monitoring, especially regarding hazardous and toxic pollutants, the detection of bacterial or fungal metabolites, or food quality assurance. In this sense, the present Special Issue aims to bring to the forefront the most important and innovative studies currently developed in various scientific areas.

This Special Issue is devoted to volatile organic compounds (VOCs) and metabolites and their roles from environment to health. Therefore, the topics that will be covered include, but are not limited to, techniques and studies developed on VOCs; metabolites and compounds produced by organisms as a response to environmental stressors, such as pollution, climate change, and diseases; and also food safety and other health-related issues.

Dr. Valentina Vassilenko
Dr. Mário Diniz
Dr. Regina Duarte
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • volatile organic compounds
  • VOCs
  • metabolites
  • environment
  • health
  • food analysis
  • analytical techniques
  • breath analysis

Published Papers (1 paper)

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Research

14 pages, 3341 KiB  
Article
Suitability of Short- and Long-Term Storage of Volatile Organic Compounds Samples in Syringe-Based Containers: A Comparison Study
by Paulo Henrique Costa Santos, Pedro Catalão Moura and Valentina Vassilenko
Metabolites 2023, 13(8), 903; https://doi.org/10.3390/metabo13080903 - 02 Aug 2023
Cited by 2 | Viewed by 663
Abstract
The employment of advanced analytical techniques and instrumentation enables the tracing of volatile organic compounds (VOCs) in vestigial concentrations (ppbv-pptv range) for several emerging applications, such as the research of disease biomarkers in exhaled air, the detection of metabolites in several biological processes, [...] Read more.
The employment of advanced analytical techniques and instrumentation enables the tracing of volatile organic compounds (VOCs) in vestigial concentrations (ppbv-pptv range) for several emerging applications, such as the research of disease biomarkers in exhaled air, the detection of metabolites in several biological processes, and the detection of pollutants for air quality control. In this scope, the storage of gaseous samples is crucial for preserving the integrity and stability of the collected set of analytes. This study aims to assess the suitability of three commercially available syringes as air containers (AC) that are commonly used for the collection, storage, isolation, and transportation of samples: glass syringes with glass plungers (AC1), and two plastic syringes, one with plastic plungers (AC2), and one with rubbered plungers (AC3). For this purpose, 99 air samples with different times of storage (from 10 min to 24 h) were analyzed using a Gas Chromatography—Ion Mobility Spectrometry device and the degradation of the samples was properly assessed by comparing the changes in the VOCs’ emission profiles. The quality of the method was assured by via the measurement of the blank’s spectra before each experimental run, as well as by the consecutive measurement of the three replicates for each sample. A statistical analysis of the changes in the VOCs’ emission patterns was performed using principal component analysis (PCA). The results, with a total explained variance of 93.61%, indicate that AC3 is the most suitable option for the long-term storage of air samples. Thus, AC3 containers demonstrated a higher capacity to preserve the stability and integrity of the analytes compared to AC1 and AC2. The findings of the short-term effects analysis, up to 1 h, confirm the suitability of all analyzed syringe-based containers for sample-transferring purposes in onsite analysis. Full article
(This article belongs to the Special Issue VOC Metabolites from Environment to Health)
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