Advanced Metabolic Profiling via Gas Chromatography–Mass Spectrometry and Liquid Chromatography–Mass Spectrometry

Dear Colleagues,

In the intricate world of metabolic research, the techniques of Gas Chromatography–Mass Spectrometry (GC–MS) and Liquid Chromatography–Mass Spectrometry (LC–MS) have proven to be more than analytical tools; they are pivotal catalysts in our quest to decode the complex narrative of biological systems. This Special Issue, "Advanced Metabolic Profiling via Gas Chromatography–Mass Spectrometry and Liquid Chromatography–Mass Spectrometry", seeks to spotlight the transformative impact these methodologies have on our ability to advance our understanding of metabolic pathways and their multifaceted implications.

GC–MS and LC–MS have revolutionized metabolic profiling, offering unparalleled specificity, sensitivity, and versatility in detecting and quantifying metabolites. These techniques stand at the forefront of metabolic research, enabling scientists to unravel the complexities of the metabolome with remarkable precision. The ability of GC–MS to separate and analyze volatile and semi-volatile compounds, coupled with the versatility of LC–MS to manage a broad spectrum of polar and nonpolar compounds, has significantly broadened the horizon of metabolic studies, facilitating comprehensive analyses that were once deemed challenging.

The relevance of these techniques extends beyond the bounds of academic curiosity; they are instrumental in addressing real-world challenges across various sectors. In healthcare, they are transforming disease diagnosis and drug development, offering insights into biomarker discovery and therapeutic interventions. In environmental science, they serve as crucial tools for monitoring pollutants and deciphering ecological dynamics. In the food industry, they ensure safety and quality, upholding the highest standards of consumer health and product integrity.

This Special Issue is a call upon researchers and innovators who are exploring the potentials of GC–MS and LC–MS to push the boundaries of metabolic research. We invite you to contribute original research articles or comprehensive review papers that not only highlight methodological advancements but also demonstrate how these techniques enhance our understanding of biological, environmental, and societal aspects. By sharing your cutting-edge research, you are contributing to a critical discourse that has the power to reshape industries, inform policymaking, and ultimately improve lives. Our aim is to compile a repository of the most innovative and impactful research in this field. Your insights and findings will be invaluable, serving as a cornerstone for future exploration and discovery.

Dr. Ana Margarida Araújo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• chromatographic methods
• mass spectrometry techniques
• metabolic profiling
• methodological advancements
• biomarker discovery
• environmental monitoring
• food safety and quality
• clinical diagnosis
• drug development