Unlocking the Mysteries of Muscle Metabolism in the Animal Sciences
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Animal Metabolism".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 1318
Special Issue Editors
Interests: muscle; metabolism; fiber type; biochemistry; mitochondria; nutrition; energy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The sustainability and security of the meat industry is predicated on the ability to grow animals as efficiently as possible. Indeed, great progress has been realized in animal growth efficiency over the past several decades, primarily through improved nutrition and genetics, and the use of growth promotants, though the latter technology is facing some pushback. Even so, as incremental increases in efficiency become more difficult to achieve through traditional means, we must continue to delve further into the cellular mechanisms controlling growth if we wish to meet the global demands for a highly coveted, yet nutritious source of protein for the human diet. Muscle growth or meat production is a complex biological process that results from the orchestration of a hierarchy of anabolic and catabolic events that are tightly synchronized with nutrient availability. When muscle cells ‘sense’ that energy substrates and amino acids are available, protein accretion and muscle growth proceeds. Conversely, when nutrient assets are limiting, either through gaps in management strategies, or during times of redirected nutrient partitioning as is the case with compromised health status or heat stress, muscle growth is curtailed, or even reversed if the insult is severe enough. To address these varied stimuli, muscle cells utilize highly integrated signaling cascades to sense and respond to nutritional cues in their residential niches. The existence and integration of these pathways are poorly understood but identification of novel processes will further empower animal scientists to monitor changes in metabolic status of growing tissues and inevitably foster discovery of new strategies for improving the efficiency of animal growth.
Prof. Dr. David E. Gerrard
Dr. Sally E. Johnson
Guest Editors
Manuscript Submission Information
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Keywords
- muscle
- amino acid metabolism
- energy metabolism
- metabolites
- protein
- growth
