Application of Medical Imaging of the Cardiovascular System in Science and Practice, Volume Ⅱ

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 4063

Special Issue Editor


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Guest Editor
1. Division of Environmental Health and Occupational Medicine, Wroclaw Medical University, Wroclaw, Poland
2. Centre for Diagnostic Imaging, 4th Military Hospital, Wroclaw, Poland
Interests: diagnostic imaging; cardiac computer tomography; cardiac magnetic resonance; CT and MR angiography; environmental health; occupational medicine; cardiovascular epidemiology and prevention
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Special Issue Information

Dear Colleagues,

Cardiovascular disease is the leading cause of death worldwide. In 2016, cardiovascular diseases accounted for 34.2% of all recorded deaths. Despite the progress in diagnostics and therapy, ischemic heart disease, stroke, and hypertensive heart disease are still significant causes of cardiovascular mortality.

Diagnostic imaging is currently the key diagnostic method for cardiovascular diseases. Echocardiography, Doppler ultrasonography and invasive coronary angiography have been the basis of diagnostic schemes of cardiovascular diseases for many years.

In recent years, we have observed a further increase in the clinical importance of subsequent imaging methods—cardiac computed tomography, cardiac magnetic resonance and CT or MR angiography. It is impossible to imagine modern medicine without the aforementioned diagnostic methods, and the perspective of the next few years will only strengthen this tendency.

We invite you to publish original research and review articles on the use and importance of cardiovascular imaging in research and clinical practice.

Dr. Paweł Gać
Guest Editor

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Keywords

  • cardiac computer tomography
  • cardiac magnetic resonance
  • CT and MR angiography
  • coronary artery diseases
  • stroke
  • arterial hypertension
  • cardiomyopathy
  • cardiovascular disease

Published Papers (2 papers)

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20 pages, 2217 KiB  
Review
Current Toolset in Predicting Acute Coronary Thrombotic Events: The “Vulnerable Plaque” in a “Vulnerable Patient” Concept
by Maria Emfietzoglou, Michail C. Mavrogiannis, Hector M. García-García, Kimon Stamatelopoulos, Ioannis Kanakakis and Michail I. Papafaklis
Life 2023, 13(3), 696; https://doi.org/10.3390/life13030696 - 4 Mar 2023
Cited by 1 | Viewed by 1676
Abstract
Despite major advances in pharmacotherapy and interventional procedures, coronary artery disease (CAD) remains a principal cause of morbidity and mortality worldwide. Invasive coronary imaging along with the computation of hemodynamic forces, primarily endothelial shear stress and plaque structural stress, have enabled a comprehensive [...] Read more.
Despite major advances in pharmacotherapy and interventional procedures, coronary artery disease (CAD) remains a principal cause of morbidity and mortality worldwide. Invasive coronary imaging along with the computation of hemodynamic forces, primarily endothelial shear stress and plaque structural stress, have enabled a comprehensive identification of atherosclerotic plaque components, providing a unique insight into the understanding of plaque vulnerability and progression, which may help guide patient treatment. However, the invasive-only approach to CAD has failed to show high predictive value. Meanwhile, it is becoming increasingly evident that along with the “vulnerable plaque”, the presence of a “vulnerable patient” state is also necessary to precipitate an acute coronary thrombotic event. Non-invasive imaging techniques have also evolved, providing new opportunities for the identification of high-risk plaques, the study of atherosclerosis in asymptomatic individuals, and general population screening. Additionally, risk stratification scores, circulating biomarkers, immunology, and genetics also complete the armamentarium of a broader “vulnerable plaque and patient” concept approach. In the current review article, the invasive and non-invasive modalities used for the detection of high-risk plaques in patients with CAD are summarized and critically appraised. The challenges of the vulnerable plaque concept are also discussed, highlighting the need to shift towards a more interdisciplinary approach that can identify the “vulnerable plaque” in a “vulnerable patient”. Full article
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Case Report
Hypertrophic Cardiomyopathy with Biventricular Involvement and Coronary Anomaly: A Case Report
by Ylenia Bartolacelli, Simone Bonetti, Anna Balducci, Ambra Bulgarelli, Luca Ragni and Andrea Donti
Life 2022, 12(10), 1608; https://doi.org/10.3390/life12101608 - 14 Oct 2022
Cited by 1 | Viewed by 1952
Abstract
Although hypertrophic cardiomyopathy (HCM) is classically considered a disease of the left ventricle, right ventricular (RV) involvement has also been reported, though still not extensively characterized. We present a case of biventricular HCM with significant RV involvement in the absence of a left [...] Read more.
Although hypertrophic cardiomyopathy (HCM) is classically considered a disease of the left ventricle, right ventricular (RV) involvement has also been reported, though still not extensively characterized. We present a case of biventricular HCM with significant RV involvement in the absence of a left intraventricular gradient: RV outflow tract gradient due to hypertrophy and near obliteration of the RV cavity. Significant RV hypertrophy may cause reduced RV diastolic filling and/or RV outflow obstruction, with potentially increased incidence of symptoms of heart failure, arrhythmias, and pulmonary thromboembolism. The optimal treatment for these patients is unclear. Our patient underwent complete treatment and elimination of right ventricular obstruction, resulting in improved symptoms and a significant reduction in postoperative gradients. Direct relief of outflow tract obstruction can be achieved with low morbidity and good intermediate- to long-term results. Conventional surgery may provide significant symptomatic improvement and should thus be considered in the setting of HCM with outflow obstruction. Full article
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