Proteotranscriptomics-Guided Research on Insects and Arachnids Toxins
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Proteins and Proteomics".
Deadline for manuscript submissions: closed (24 March 2023) | Viewed by 2053
Special Issue Editors
Interests: bioinformatics; transcriptomics; venomics; proteomics; next-gen sequencing
Interests: proteomics; next generation sequencing; arthropod parasites; protease inhibitors; disease vectors; cystatin; serpin; kunitz; tick; insect; vector-host interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Venoms are rich cocktails of active peptides, proteins, and enzymes that are very commonly used by various species to capture their prey or defend themselves. In most cases, these toxic secretions from one organism are injected into the internals of another organism through a mechanical injury. The exploration of venoms and their selected components—resulting from decades of evolution—have revealed dozens of therapeutically active and promising drug candidates. This exploration has implied various technical approaches, among which proteomics, transcriptomics, and bioinformatics are today in pole position. In this Special Issue, we first want to highlight and demonstrate—once again and again if necessary—how valuable molecules issued from insects and arthropods venoms can be for new drug candidate discovery. Since insects and arthropods account for most species of eukaryotic life on Earth, it seems obvious to expect that the richness of their venom arsenal is far from being completely explored. Second, this Special Issue aims to promote innovative results from research conducted on “noncommon” species focusing on the venom role in species adaptation. We therefore expect authors to share complete and exciting evidence of valuable action of discovered or optimized molecules.
Dr. Dominique Kadio Koua
Dr. Michail Kotsyfakis
Guest Editors
Manuscript Submission Information
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Keywords
- insect toxins
- arachnid toxins
- venom gland transcriptomics
- venom proteomics
- therapeutic valorization of venom components
