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Life
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Exploration of the Unmet Needs of Aging People Living with...
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Exploration of the Unmet Needs of Aging People Living with HIV

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Epidemiology".

Deadline for manuscript submissions: closed (15 July 2023) | Viewed by 3106

Special Issue Editors

Dr. Maile Young Karris

E-Mail Website
Guest Editor
Center for Innovative Phage Applications and Therapeutics, Division of Infectious Diseases and Global Public Health, University of California, San Diego, CA 92093, USA
Interests: HIV and aging; loneliness; frailty; chronic pain; social disparities of health
Prof. Dr. Anjali Sharma

E-Mail Website
Guest Editor
Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10467, USA
Interests: metabolic conditions; HIV in women; substance use; frailty

Special Issue Information

Dear Colleagues,

The advent of easier-to-access, tolerable, and conveniently dosed antiretroviral therapy enhances the ability of people living with HIV (PLWH) to experience a long life. However, aging PLWH face new challenges, including the management of HIV-associated, non-AIDS co-morbidities, including geriatric syndromes, social isolation, mental health concerns, and ongoing substance use. In turn, these conditions, combined with social disparities of health, including intersecting stigmas and poverty, contribute to impaired physical, mental, and cognitive function. This special edition will highlight these highly prevalent and relevant topics with a specific focus on areas prioritized by aging PLWH and work involving community-based participatory research.  

Dr. Maile Young Karris
Prof. Dr. Anjali Sharma
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • HIV and aging
  • social isolation
  • co-morbidities
  • social disparities of health
  • geriatric syndromes
  • community-priorities

Published Papers (3 papers)

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Research

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12 pages, 638 KiB  
Article
Ageing People Living with HIV/AIDS, PLWHA; More Dental Challenges; the Romanian Dental Professional’s Point of View
by Florentina Caministeanu, Loredana Sabina Cornelia Manolescu, Mădălina Adriana Malița, Viorel Ștefan Perieanu, Elena Cristina Marcov, Iuliana Babiuc, Camelia Ionescu, Cristina Florentina Pîrvu, Radu Catalin Costea, Ioana Voinescu, Liliana Burlibasa, Irina Prasacu and Mihai Burlibasa
Life 2023, 13(5), 1096; https://doi.org/10.3390/life13051096 - 27 Apr 2023
Viewed by 1123
Abstract
Background: In Romania, HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome) were first acknowledged in 1989. Getting older with HIV/AIDS is now possible due to antiretroviral treatment, but it can bring dental problems due to HIV itself or to the reluctance of [...] Read more.
Background: In Romania, HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome) were first acknowledged in 1989. Getting older with HIV/AIDS is now possible due to antiretroviral treatment, but it can bring dental problems due to HIV itself or to the reluctance of dental professionals to treat dental problems. Our study aims to assess the attitudes, knowledge, and practices of Romanian dental professionals regarding aging PLWHA. Methods: An analytical cross-sectional observational survey based on a self-administered questionnaire was conducted for Romanian dental professionals from October 2022 to January 2023. Results: The responders’ group profile was as follows: a mean age of 39.09 ± 0.36 years (limit: 19–75), a majority of 991 (90.01%) from urban dental offices, and 364 (33.06%) with more than twenty years’ experience. A total of 517 (46.95%) responders had an unprofessional attitude and declared that, if possible, they would avoid taking part in performing dental treatments for people living with HIV/AIDS (PLWHA). There were 89 (8.08%) dental professionals that refused to work with PLWHA. Only 363 (32.97%) had worked with one previously. The dental professionals in rural areas refused PLWHA more frequently: 20% (N = 22) of rural dental professionals vs. 6.76% (N = 67) of urban dental professionals refused to work with PLWHA (OR = 0.30; 95% CI: 0.16-.56). The logistic regression applied for the 1101 responders revealed after stepwise selection that the most influential factor for their refusal to work with PLWHA in our study group was being previously exposed to HIV during dental practice (OR = 14.45; 95% CI: 8.55- 24.42; p = 0.000). Conclusions: Dental educators and health care planners should promote the knowledge of prophylaxis and positive attitudes towards the treatment of PLWHA. Successful resolution of these concerns is time consuming and expensive but necessary if dentists are to satisfy their professional obligations to HIV/AIDS patients. Full article
(This article belongs to the Special Issue Exploration of the Unmet Needs of Aging People Living with HIV)
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11 pages, 419 KiB  
Article
Sexually Transmitted Infections Prevalence and Cascade of Care among Undocumented Sex Workers: A Twenty-Year-Long Experience
by Alessandra Donisi, Agnese Colpani, Beatrice Zauli, Andrea De Vito, Vito Fiore, Sergio Babudieri and Giordano Madeddu
Life 2023, 13(3), 606; https://doi.org/10.3390/life13030606 - 22 Feb 2023
Cited by 3 | Viewed by 1289
Abstract
Undocumented migrant sex-workers (SW) are vulnerable to Sexually Transmitted Infections (STIs). However, data regarding prevalence and linkage-to-care are lacking. Defining epidemiology is crucial to implement preventive measures. We report data from SW attending a facility for migrants in Piacenza, Italy. We collected medical [...] Read more.
Undocumented migrant sex-workers (SW) are vulnerable to Sexually Transmitted Infections (STIs). However, data regarding prevalence and linkage-to-care are lacking. Defining epidemiology is crucial to implement preventive measures. We report data from SW attending a facility for migrants in Piacenza, Italy. We collected medical records from 1999 until 2021. Quantitative variables were summarized as mean and standard deviation (SD), and qualitative ones by absolute and relative frequencies. Logistic regression analysis was performed to assess the relationship between sociodemographic, clinical variables, positive testing, and loss to follow-up (LFU). Overall, 1035 STI episodes were collected, 917 in cisgender-females (CF), and 118 in transgender-females (TF). Overall, 474 diagnoses were made. Three-hundred-ninety-two/474 (82.7%) started therapy, and 264/474 (55.7%) complied with a follow-up. Only 51.5% of HBV and 30.8% of HIV were linked to care. Having symptoms (OR 1.70 (95% CI 1.06–2.73), p = 0.028) and previous STIs (OR 1.36 (95% CI 1.04–1.77), p = 0.022) were associated with a higher chance of STIs, while at-risk intercourse to lower risk (OR 0.19 (95% CI 0.07–0.49), p = 0.001). TF had higher odds of bloodborne infections and syphilis (OR 2.61 (95% CI 1.17–5.80), p = 0.019). Regarding follow-up, the older the patient, the higher the LFU (OR 1.05 (95% CI 1.01–1.10), p = 0.021). Our data showed a high prevalence of STIs and LFU among undocumented SW. TF are even more vulnerable. Further efforts should be put into targeted interventions. Full article
(This article belongs to the Special Issue Exploration of the Unmet Needs of Aging People Living with HIV)
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Review

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16 pages, 323 KiB  
Review
Immunological and Clinical Responses to Vaccinations among Adults Living with HIV
by Carlo Bieńkowski, Zuzanna Żak, Filip Fijołek, Martyna Cholewik, Maciej Stępień, Agata Skrzat-Klapaczyńska and Justyna D. Kowalska
Life 2024, 14(5), 540; https://doi.org/10.3390/life14050540 - 24 Apr 2024
Viewed by 343
Abstract
People living with human immunodeficiency virus (HIV) are at higher risk of morbidity and mortality due to vaccine-preventable diseases. At the same time, they are less likely to respond to vaccinations, and might have a higher rate of vaccine adverse event and faster [...] Read more.
People living with human immunodeficiency virus (HIV) are at higher risk of morbidity and mortality due to vaccine-preventable diseases. At the same time, they are less likely to respond to vaccinations, and might have a higher rate of vaccine adverse event and faster waning of protective effect. International and national guidelines emphasize the importance of vaccinating people living with HIV against respiratory system disease pathogens including seasonal influenza, Streptococcus pneumoniae, and COVID-19, as well as against sexually transmitted infections, i.e., Hepatitis A and B (HAV, HBV) and human papillomavirus (HPV). This narrative review aims to provide a comprehensive examination of the current knowledge regarding the immune and clinical responses elicited by vaccinations in the older adult population living with HIV. Full article
(This article belongs to the Special Issue Exploration of the Unmet Needs of Aging People Living with HIV)
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