Special Issue "Extraction, Characterization, and Application of Valuable Biologically Active Substances from Plants"

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Plant Science".

Deadline for manuscript submissions: 31 July 2023 | Viewed by 2488

Special Issue Editors

Laboratory of Biocatalysis, Kemerovo State University, 650043 Kemerovo, Russia
Interests: biologically active substances; extraction methods; natural sources; structure; in vitro cell cultures
Institute of Civil Engineering, Peter the Great St. Petersburg Polytechnic University, 195251 Saint-Petersburg, Russia
Interests: antioxidant activity; free radicals; medicinal plants; biotechnology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plants are producers of many biologically active substances (BAS)—compounds capable of influencing biological processes in the body. Such compounds include cardiac glycosides, saponins, sterols, carotenoids, polyphenols, alkaloids, vitamins, quinones, and substances with a specific aroma, taste, and color. Biologically active substances are the products of secondary metabolism, which are called secondary metabolites or secondary products of biosynthesis. More than 100,000 secondary metabolites produced by plants are currently known. Many of them are practically and economically important products and used in the pharmaceutical, cosmetic, and food industries. This Special Issue aims to publish research articles and reviews that focus on the identification of new plant sources of valuable biologically active substances, their structural, physicochemical and rheological characterization, the processes used to extract and purify them, and their biological properties.

Dr. Alexander Prosekov
Prof. Dr. Natalia Politaeva
Guest Editors

Manuscript Submission Information

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Keywords

  • biologically active substances
  • extracts
  • plants materials
  • medicinal plants
  • antioxidant activity
  • nutraceuticals
  • algae

Published Papers (3 papers)

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Research

Article
Chemical Composition and Biological Activities of Centranthus longiflorus Stems Extracts Recovered Using Ired-Irrad®, an Innovative Infrared Technology, Compared to Water Bath and Ultrasound
Life 2023, 13(6), 1288; https://doi.org/10.3390/life13061288 - 30 May 2023
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Abstract
Extraction of polyphenols from Centranthus longiflorus stems was conducted using ultrasound and infrared Ired-Irrad® techniques, and compared to the conventional water bath method. Response surface methodology was used to analyse the effect of time, temperature, and ethanol percentage, as well as to [...] Read more.
Extraction of polyphenols from Centranthus longiflorus stems was conducted using ultrasound and infrared Ired-Irrad® techniques, and compared to the conventional water bath method. Response surface methodology was used to analyse the effect of time, temperature, and ethanol percentage, as well as to optimize the three extraction methods. The highest phenolic content (81 mg GAE/g DM) and antioxidant activity (76% DPPH inhibition) were recorded with the Ired-Irrad® extract obtained under the optimal conditions: 55 °C, 127 min, 48% (v/v) ethanol. Biological activities (antioxidant, antibacterial and antibiofilm) of the three extracts were assessed. All C. longiflorus stems extracts showed limited antibacterial effects regardless of the extraction method (MIC = 50 mg/mL), whereas Ired-Irrad® extract exhibited the highest biofilm eradication and prevention capacities (93% against Escherichia coli and 97% against Staphylococcus epidermidis, respectively). This bioactivity is likely related to abundant caffeoylquinic acid and quercetin rutinoside, as identified by RP-UHPLC-PDA-MS analysis. The results obtained further promote the effectiveness of Ired-Irrad® as a highly flexible and cost-efficient extraction technique. Full article
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Article
Influence of Extraction Techniques and Solvents on the Antioxidant and Biological Potential of Different Parts of Scorzonera undulata
Life 2023, 13(4), 904; https://doi.org/10.3390/life13040904 - 29 Mar 2023
Viewed by 542
Abstract
The genus Scorzonera has various medicinal values. Species belonging to this genus were traditionally used as drugs or in food. The current study aimed to determine the phytochemical composition, antioxidant activity, and biological properties of the tuber, leaf, and flower of Scorzonera undulata [...] Read more.
The genus Scorzonera has various medicinal values. Species belonging to this genus were traditionally used as drugs or in food. The current study aimed to determine the phytochemical composition, antioxidant activity, and biological properties of the tuber, leaf, and flower of Scorzonera undulata extracts, collected from the southwest of Tunisia. Phenolic compounds from the three parts were extracted using two solvents (water and ethanol) and two extraction techniques (maceration and ultrasound). The total phenolic content was measured by the Folin–Ciocalteu assay. Furthermore, the chemical composition of Scorzonera undulata extract was also investigated by the LC-ESI–MS method using phenolic acid and flavonoid standards. The variation of the extraction methods induced a variation in the real potentialities of the three parts in terms of bioactive molecules. However, the aerial part of S. undulata (leaves and flowers) showed, in general, the highest phenolic contents. Twenty-five volatile compounds have been detected by GC-MS in S. undulata extracts; among them, fourteen were identified before derivatization. The DPPH test showed that the aerial part of the plant has a higher antioxidant activity compared to the tuber (25.06% at 50 µg/mL for the leaf ethanolic extract obtained by ultrasound extraction). For most biological activities (anti-Xanthine, anti-inflammatory, and antidiabetic (alpha-amylase and alpha-glucosidase)), the aerial parts (flowers and leaves) of the plant showed the highest inhibition than tubers. Full article
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Article
Ultrasonic-Assisted Extraction and Antioxidant Potential of Valuable Protein from Ulva rigida Macroalgae
Life 2023, 13(1), 86; https://doi.org/10.3390/life13010086 - 28 Dec 2022
Cited by 1 | Viewed by 1199
Abstract
Ulva green macroalgae or sea lettuce are rich sources of protein with nutritional benefits that promote health as a future plant-based functional ingredient in the food industry. Alkaline pretreatment improved ultrasonic-assisted protein extraction from Ulva rigida biomass. Parameters affecting ultrasonic-assisted extraction of protein [...] Read more.
Ulva green macroalgae or sea lettuce are rich sources of protein with nutritional benefits that promote health as a future plant-based functional ingredient in the food industry. Alkaline pretreatment improved ultrasonic-assisted protein extraction from Ulva rigida biomass. Parameters affecting ultrasonic-assisted extraction of protein were type of solvent, biomass-solvent ratio, biomass preparation and extraction cycle. In vitro digestibility was evaluated from oven- and freeze-dried biomass. Results showed highest concentration and extraction yield of protein from U. rigida using alkaline rather than acid and distilled water. A high biomass–solvent ratio at 1:10 or 0.1 g mL−1 increased protein extraction. Higher alkaline concentration increased protein extraction. Highest protein extractability was 8.5% dry matter from freeze-dried U. rigida biomass, with highest protein extraction and antioxidant activity from extraction of U. rigida macroalgae at high alkaline concentrations. U. rigida macroalgae oven-dried biomass presented suitable human digestibility. Efficient pretreatment of U. rigida maximized protein hydrolysate and bioactive peptide production for wide-ranging applications. Full article
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