Clinical Application of Cardiac Imaging

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 1554

Special Issue Editors


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Guest Editor
Department of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy
Interests: heart failure; acute heart failure; valvular heart disease; echocardiography; advanced echocardiography; clinical cardiology; cardiovascular medicine

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Guest Editor
1. Department of Cardiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
2. Department of Cardiology, Haga Teaching Hospital, 2545 GM The Hague, The Netherlands
Interests: echocardiography; cardiac imaging; cardiac MRI; cardiac CT; cardiovascular imaging; transesophageal echocardiography; transthoracic echocardiography
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Special Issue Information

Dear Colleagues,

Cardiac imaging is a pivotal tool in the diagnosis, management, and treatment of cardiovascular diseases. Its non-invasive or minimally invasive nature makes it a safe and effective option for patients, possessing considerable accuracy compared to invasive techniques. Clinicians should consider cardiac imaging in their diagnostic and treatment pathways for patients with suspected or confirmed cardiovascular disease.

The Special Issue, entitled “Clinical Application of Cardiac Imaging", explores various imaging techniques and their application in the diagnostic and prognostic assessment of cardiovascular diseases. It further discusses the role of multimodality imaging in guiding therapeutic management and interventions, such as cardiac catheterization, electrophysiology studies, and heart surgery, addressing topics such as echocardiography, cardiac magnetic resonance imaging, computed tomography, and nuclear imaging.

Overall, this Special Issue aims to provide a platform for researchers to share their latest findings related to the current state of cardiac imaging and its clinical applications. It will demonstrate the significance of various imaging modalities in the diagnosis and management of cardiac disease, discuss the recent advances in scientific knowledge and highlight the need for continued research and innovation in this field, and address the challenges and limitations of cardiac imaging.

Dr. Maria Concetta Pastore
Dr. Marco Guglielmo
Guest Editors

Manuscript Submission Information

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Keywords

  • cardiac imaging
  • echocardiography
  • magnetic resonance imaging
  • computed tomography
  • nuclear imaging
  • heart failure
  • valvular heart disease
  • congenital heart disease

Published Papers (2 papers)

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Research

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12 pages, 2002 KiB  
Article
Diagnostic Ability of Manual Calcification Length Assessment on Non-Electrocardiographically Gated Computed Tomography for Estimating the Presence of Coronary Artery Disease
by Ryota Watanabe, Yuichi Saito, Satoshi Tokimasa, Hiroyuki Takaoka, Hideki Kitahara, Masato Yamanouchi and Yoshio Kobayashi
J. Clin. Med. 2024, 13(8), 2255; https://doi.org/10.3390/jcm13082255 - 12 Apr 2024
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Abstract
Background: Coronary artery calcification score (CACS) on electrocardiography (ECG)-gated computed tomography (CT) is used for risk stratification of atherosclerotic cardiovascular disease, which requires dedicated analytic software. In this study, we evaluated the diagnostic ability of manual calcification length assessment on non-ECG-gated CT for [...] Read more.
Background: Coronary artery calcification score (CACS) on electrocardiography (ECG)-gated computed tomography (CT) is used for risk stratification of atherosclerotic cardiovascular disease, which requires dedicated analytic software. In this study, we evaluated the diagnostic ability of manual calcification length assessment on non-ECG-gated CT for epicardial coronary artery disease (CAD). Methods: A total of 100 patients undergoing both non-ECG-gated plain CT scans with a slice interval of 1.25 mm and invasive coronary angiography were retrospectively included. We manually measured the length of the longest calcified lesions of coronary arteries on each branch. The relationship between the number of coronary arteries with the length of coronary calcium > 5, 10, or 15 mm and the presence of epicardial CAD on invasive angiography was evaluated. Standard CACS was also evaluated using established software. Results: Of 100 patients, 49 (49.0%) had significant epicardial CAD on angiography. The median standard CACS was 346 [7, 1965]. In both manual calcium assessment and standard CACS, the increase in calcium burden was progressively associated with the presence of epicardial CAD on angiography. The receiver operating characteristic curve analysis showed similar diagnostic abilities of the two diagnostic methods. The best cut-off values for CAD were 2, 1, and 1 for the number of vessels with calcium > 5, 10, and 15 mm, respectively. Overall, the diagnostic ability of manual calcium assessment was similar to that of standard CACS > 400. Conclusions: Manual assessment of coronary calcium length on non-ECG-gated plain CT provided similar diagnostic ability for the presence of significant epicardial CAD on invasive angiography, as compared to standard CACS. Full article
(This article belongs to the Special Issue Clinical Application of Cardiac Imaging)
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Review

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14 pages, 1219 KiB  
Review
Dynamic CT Myocardial Perfusion: The Role of Functional Evaluation in the Diagnosis of Coronary Artery Disease
by Agata Zdanowicz, Maciej Guzinski, Michal Pula, Agnieszka Witkowska and Krzysztof Reczuch
J. Clin. Med. 2023, 12(22), 7062; https://doi.org/10.3390/jcm12227062 - 13 Nov 2023
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Abstract
Coronary computed tomography angiography (CTA) is a widely accepted, non-invasive diagnostic modality for the evaluation of patients with suspected coronary artery disease (CAD). However, a limitation of CTA is its inability to provide information on the hemodynamic significance of the coronary lesion. The [...] Read more.
Coronary computed tomography angiography (CTA) is a widely accepted, non-invasive diagnostic modality for the evaluation of patients with suspected coronary artery disease (CAD). However, a limitation of CTA is its inability to provide information on the hemodynamic significance of the coronary lesion. The recently developed stress dynamic CT perfusion technique has emerged as a potential solution to this diagnostic challenge. Dynamic CT myocardial perfusion provides information on the hemodynamic consequences of coronary stenosis and is used to detect myocardial ischemia. The combination of stress dynamic CT myocardial perfusion with CTA provides a comprehensive assessment that integrates anatomical and functional information. CT myocardial perfusion has been validated in several clinical studies and has shown comparable accuracy to Positron Emission Tomography (PET) and stress magnetic resonance imaging (MRI) in the diagnosis of hemodynamically significant coronary stenosis and superior performance to Single Photon Emission Computed Tomography (SPECT). More importantly, CTP-derived myocardial perfusion has been shown to have a strong correlation with FFR, and the use of CTP results in a reduction of negative catheterizations. In the context of suspected stable coronary artery disease, the CT protocol with dynamic perfusion imaging combined with CTA eliminates the need for additional testing, making it a convenient “one-stop-shop” method and an effective gatekeeper to an invasive approach. Full article
(This article belongs to the Special Issue Clinical Application of Cardiac Imaging)
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