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Special Issue "Cardiovascular Computed Tomography in Clinical Practice"

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1. Department of Cardiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
2. Department of Cardiology, Haga Teaching Hospital, 2545 GM The Hague, The Netherlands
Interests: echocardiography; cardiac imaging; cardiac MRI; cardiac CT; cardiovascular imaging; transesophageal echocardiography; transthoracic echocardiography
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Dr. Ibrahim Danad

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Department of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
Interests: coronary artery disease; coronary angiography; interventional cardiology; diagnostic imaging; PCI; PET imaging; cardiac catheterization; cardiac imaging; PET; cardiology

Dr. Saima Mushtaq

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Department of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Via C. Parea 4, 20138, Milan, Italy
Interests: cardiac CT; cardiac MRI; invasive coronary angiography; fractional flow reserve; angina; microcirculation
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Special Issue Information

Dear Colleagues,

During the last 20 years, cardiac computed tomography (CCT) has emerged as a technique that can provide crucial diagnostic and prognostic information in different clinical scenarios. CCT is now recommended by the international scientific society as a key tool in patients with acute and chronic coronary artery disease (CAD). CCT cannot only rule out obstructive CAD, but also provides valuable information about the atherosclerotic burden, plaque composition, and pericoronary fat inflammation. Moreover, recent developments such as the study of myocardial perfusion and fractional flow reserve have transformed CCT into a one-stop test able to offer all the anatomical and functional information to guide the management of patients with CAD. CCT is also increasingly used in other clinical settings, such as congenital and structural heart disease. Finally, there is increasing evidence that CCT can be used for tissue characterization with remarkable clinical value, including the assessment of ischemic and non-ischemic cardiomyopathies.

This Special Issue aims to discuss the potential and challenges of new and established clinical applications of cardiovascular CT.

Dr. Marco Guglielmo
Dr. Ibrahim Danad
Dr. Saima Mushtaq
Guest Editors

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Keywords

cardiac computed tomography (CCT)
coronary artery disease
structural heart disease
congenital heart disease
atherosclerosis
plaque composition
pericoronary fat inflammation
ischemic and non-ischemic cardiomyopathies

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Open AccessArticle

Morphology and Anatomical Classification of Pericardial Cavities: Oblique and Transverse Sinuses

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J. Clin. Med. 2023, 12(13), 4320; https://doi.org/10.3390/jcm12134320 - 27 Jun 2023

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Abstract

The pericardial sinuses are an important anatomical feature of the pericardial cavity, however, their clinical anatomy has not been thoroughly studied. In this study, we aim to provide the first classification of the oblique and transverse sinuses. We analyzed 121 computer tomography scans (46.3% female, age of 66 ± 12 years) of the pericardial cavity. The oblique sinuses were classified into four types: 1 (shallow with narrow entrance), 2 (shallow with wide entrance), 3 (deep with narrow entrance), and 4 (deep with wide entrance). The transverse sinuses were classified into four types: Concave, Wine-type, Straight, and Convex. The most common oblique sinus type was Type 1. The median oblique sinus volume was 8.4 (5.3) mL, the median entrance length was 33.0 (13.2) mm, and the depth was 38.2 (11.8) mm. The most common transverse sinus type was Concave. The median transverse sinus volume was 14.8 (6.5) mL, and the median length was 52.8 (17.7) mm. Our study provides an anatomical classification of the pericardial sinuses. The individual variability of the sinuses’ morphology highlights the importance of understanding the clinical topography of the sinuses, particularly for minimally invasive thoracic ablation procedures. Full article

(This article belongs to the Special Issue Cardiovascular Computed Tomography in Clinical Practice)

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The Non-Invasive Diagnosis of Chronic Coronary Syndrome: A Focus on Stress Computed Tomography Perfusion and Stress Cardiac Magnetic Resonance

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J. Clin. Med. 2023, 12(11), 3793; https://doi.org/10.3390/jcm12113793 - 31 May 2023

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Abstract

Coronary artery disease is still a major cause of death and morbidity worldwide. In the setting of chronic coronary disease, demonstration of inducible ischemia is mandatory to address treatment. Consequently, scientific and technological efforts were made in response to the request for non-invasive diagnostic tools with better sensitivity and specificity. To date, clinicians have at their disposal a wide range of stress-imaging techniques. Among others, stress cardiac magnetic resonance (S-CMR) and computed tomography perfusion (CTP) techniques both demonstrated their diagnostic efficacy and prognostic value in clinical trials when compared to other non-invasive ischemia-assessing techniques and invasive fractional flow reserve measurement techniques. Standardized protocols for both S-CMR and CTP usually imply the administration of vasodilator agents to induce hyperemia and contrast agents to depict perfusion defects. However, both methods have their own limitations, meaning that optimizing their performance still requires a patient-tailored approach. This review focuses on the characteristics, drawbacks, and future perspectives of these two techniques. Full article

(This article belongs to the Special Issue Cardiovascular Computed Tomography in Clinical Practice)

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Special Issue "Cardiovascular Computed Tomography in Clinical Practice"

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