Special Issue "Insulin Signaling and Fat Homeostasis in Metabolic and Neurodegenerative Disorders"
Deadline for manuscript submissions: closed (29 September 2022) | Viewed by 15746
Interests: metabolic disease; obesity; adipose tissue; diabetes; NAFLD
Interests: diabetes; atherosclerosis; cardiovascular disease; genetics; obesity
Interests: insulin signaling; insulin resistance; aging; Alzheimer’s disease; Down syndrome; neurodegeneration; mitochondrial bioenergetics
Special Issues, Collections and Topics in MDPI journals
Special Issue in Antioxidants: Oxidative Stress and Neurodegenerative Disorders II
Special Issue in Antioxidants: Crosstalk between Cell Redox Homeostasis and Synaptic Functions in Physiological and Pathological Conditions
Alterations of insulin signaling leading to reduced insulin sensitivity are increasingly recognized as key elements in a variety of chronic noncommunicable diseases, including diabetes, metabolic syndrome, MAFLD, and cardiovascular and neurodegenerative diseases.
In recent years, new molecular mechanisms/pathways have emerged, which increase our comprehension of how these diseases develop and progress. These advances in the field of chronic noncommunicable diseases have identified new potential mechanisms implicated in the development of these disorders (i.e., signaling molecules, adipokines, genetic, epigenetic reprogramming, new biomarkers) that could lead to the development of new approaches and pharmacological targets aimed at preventing and/or overturning these disorders and the associated complications.
The aim of this Special Issue is to bring together research papers and review articles that will drive the focus on the present knowledge in the context of chronic noncommunicable diseases, with a special focus on diabetes, metabolic syndrome, MAFLD, and cardiovascular and neurodegenerative diseases, with the purpose of better understanding the pathways involved in these alterations, and ultimately shedding light on newer approaches to prevent or reverse these diseases.
Prof. Dr. Maria Gisella Cavallo
Prof. Dr. Marco Giorgio Baroni
Prof. Dr. Eugenio Barone
Manuscript Submission Information
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- Cardiovascular alterations
- Oxidative stress
- Fat homeostasis
- Brain metabolism