New Research on Bioactive Natural Products
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 254
Special Issue Editor
Interests: CVD; atherosclerosis; endothelial dysfunction; inflammation; atherothrombosis; platelets; leukocytes; PAF; cytokines; chemokines; ADP; collagen; thrombin; anti-inflammatory; antithrombotic; anti-atherogenic; marine; fish; algae; marine plants; mollusks; shellfish; by-products; polar lipids; lipids; PUFA; MUFA; SFA; peptides; bioactives; compounds; vitamins; foods; nutraceuticals; food-supplements; pharmaceuticals; bio-pharmaceuticals; drugs
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Special Issue Information
Dear Colleagues,
Chronic disorders like cardiovascular diseases (CVD), cancer, renal and neurodegenerative disorders, allergy and autoimmune diseases, persistent infections and associated manifestations, etc., are a global burden. Even though current approaches for prevention and therapy have high efficacy, they nevertheless usually come along with high costs, undesirable side effects and environmental issues. Hence, there is an increasing necessity for developing novel products containing natural bioactives, especially those derived from sustainable natural sources.
The objective of this Special Issue is to promote research in the field and outline the current status and future perspectives on the valorization of bioactives from sustainable natural sources, such as the rich-in-natural-bioactives bio-cultures of several microorganisms and/or several by-products of the agro-food sector, as well as to highlight their importance as ingredients for the design and production of high-value, bio-functional medicinal products, including supplements, nutraceuticals and drugs, with promising health-promoting effects, against the aforementioned inflammation-related chronic disorders. Emphasis will be given to work with state-of-the-art methods of isolation and molecular analysis applied to several natural sources for obtaining/extracting and fractionating such natural micro-/macro-bioactives from the prime extracts/mixtures/filtrates/isolates/etc. derived from a sustainable natural source, as well as to the OMICS-based full chemical characterization and structural elucidation, in tandem with designed and tailored bioassays and in vitro/ex vivo/in vivo approaches, in order to evaluate structure–activity relationships and potential synergism(s) against specific bio-molecular pathways and cell/tissue/organ biological responses, which is of paramount importance in assessing structure–activity and causality, and will provide the molecular evidence for the utilization of the most optimum bio-functional natural bioactives or their mixtures for the production of targeted bio-functional products, based on current legislations and according to the needs of the industry and consumers.
Studies containing such targeted biomolecular experiments accompanied by appropriately designed approaches for evaluating the clinical safety and efficacy of products containing such natural bioactives, through tandem animal studies and clinical trials, are also welcomed. Special attention will be given to work on such sustainable natural bioactives with higher safety, efficacy and bioavailability–biodigestibility. Finally, relative reviews and meta-analysis articles in the field are also welcomed in this Special Issue.
Dr. Alexandros Tsoupras
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- chronic disorders
- bioactives
- natural sources
- sustainable sources
- biomolecular
- structure–activity relationship
- synergism
- health promoting
- bio-functional
- products
- supplements
- nutraceuticals
- drugs
