Molecular and Cellular Mechanisms of Apoptosis and Senescence
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 1143
Special Issue Editor
Interests: cell biology; antioxidants; transmembrane signalisation; actin cytoskeleton; anti-tumor therapy; cytotoxicity; apoptosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Apoptosis and senescence are two types of cellular response to damage that are observed in different pathologies as cancer, neurodegenerative diseases and aging through different mechanisms. Cellular senescence as well as apoptosis are homeostatic processes that reduce proliferation and help to prevent the propagation of damaged cells, meaning they have an essential physiological role during development. Depending on age, the above processes could function as the main mechanisms of tumor suppression, providing an effective antitumor strategy in the early and reproductive stages of life, but both become destructive and promote aging later in life.
Given the physiological and pathological roles that apoptosis and aging may play, the study of their cellular and molecular mechanisms will be beneficial in their therapeutic exploitation.
This Special Issue calls out both original articles and reviews, providing IJMS readers with an elucidation of the understanding of the molecular and cellular mechanisms of apoptosis and aging, as well as their relationship in various pathological processes, with the aim of developing new research approaches and therapeutic strategies.
Prof. Dr. Rumiana Tzoneva
Guest Editor
Manuscript Submission Information
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Keywords
- apoptosis
- cellular senescence
- cancer
- neurodegenerative diseases
