Zinc Enzymes for Drug Design and Drug Development
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 30 May 2024 | Viewed by 274
Special Issue Editors
Interests: structural biology; protein crystallography; drug design; carbonyc anhydrases
Special Issues, Collections and Topics in MDPI journals
Interests: structural biology; X-ray crystallography; biochemistry
Special Issues, Collections and Topics in MDPI journals
Interests: structural biology; X-ray crystallography; proteins; protein-ligand complexes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Zinc is an essential transition metal necessary for the activity of many enzymes involved in important biological functions. For this reason, many zinc-containing enzymes, such as Carbonic Anhydrases (CAs), Matrix Metalloproteinases (MMPs), and Histone deacetylases (HDACs), have in recent years garnered great interest as therapeutic targets for treating a wide variety of human diseases, and many successful examples of drug design studies directed at these molecules are available. In this issue, we will summarize the most important results obtained in this field and provide future perspectives for developing novel drug classes targeting zinc metalloenzymes.
Dr. Giuseppina De Simone
Dr. Anna Di Fiore
Dr. Vincenzo Alterio
Guest Editors
Manuscript Submission Information
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Keywords
- zinc enzymes
- carbonic anhydrases
- matrix metalloproteinases
- histone deacetylases
- zinc metalloenzymes
- drug design
