Microbial Resistance Mechanisms
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 6341
Interests: clinical biochemistry; anticancer drugs; cytotoxicity; gene expression; drugs diffusion; new antibacterial agents; host–pathogen interactions
Special Issues, Collections and Topics in MDPI journals
With the dramatic increase in antibiotic resistance in microbes, new knowledge regarding the mechanisms of this drug resistance is important for the development of novel therapies. These microbial resistance mechanisms focus on the modification of a drug target, its uptake limiting, and active efflux from microbial cells. Moreover, in many clinical settings, a biofilm represents a hazardous problem concerning many chronic infections involving these consortia of microbial cells enclosed by a polysaccharide matrix. A biofilm structure protects against antimicrobial agents and can stimulate their resistance mechanisms. The need for new knowledge regarding microbial resistance mechanisms seems crucial and is required for novel antibacterial agent design and applications. In an attempt to gather recent advances in this field, I aim to edit a Special Issue in the International Journal of Molecular Sciences (IF: 5.924) concerning “Microbial Resistance Mechanisms”. This Special Issue focuses on the molecular studies of microbial resistance mechanisms of planktonic or biofilm-forming cells, which might be considered as targets for new drugs action. These two topics of study are welcomed.
Dr. Michał Arabski
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- antibiotic resistance
- virulence factors
- antimicrobial agents
- lytic proteins
- metal complexes