New Antibacterial Agents
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 34104
Interests: clinical biochemistry; anticancer drugs; cytotoxicity; gene expression; drugs diffusion; new antibacterial agents; host-pathogen interactions
Special Issues, Collections and Topics in MDPI journals
The increase of antibiotic resistance in bacteria highlights the urgent need for improved antibacterial agents. There are interesting new agents with antibacterial potential but with modes of action that are not fully known, or well-known modified drugs with patterns of toxicity, effectiveness, and/or other related properties that need to be investigated. These new ways/agents are mainly targeted into bacterial virulence factors, cell division machinery, biofilm formation, or cell membrane disruption. It seems to be crucial to determine their antibacterial mechanisms and effectiveness in comparison to cytotoxicity against eukaryotic cells as a potential new agent for clinical application in the future.
Nanoparticles, naturally obtained antibacterials, synthetic or semi-synthetic agents which are chemically altered natural products, metal complexes, peptides, or bacteriophages and their lytic proteins are considered as new antibacterial agents.
In an attempt to bring together recent advances in this field, I will edit a Special Issue in the International Journal of Molecular Sciences (IF:4.556) on the topic “New Antibacterial Agents”. This Special Issue is focused on the effectiveness, mode of action, and cytotoxic activity of new antibacterial agents. Since IJMS is a journal of molecular science, pure clinical studies will not suitable for the journal. However, clinical submissions with biomolecular experiments are welcomed.
Dr. Michał Arabski
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- antibacterial agents
- antibiotic resistance
- bacterial virulence factors
- cell division machinery
- biofilm formation
- cell membrane disruption
- natural products
- metal complexes
- lytic proteins