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Special Issue "The Contribution of Proteomics and Post-mortem Laboratory Investigations in Forensic Pathology"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 30 November 2023 | Viewed by 908

Special Issue Editor

Special Issue Information

Dear Colleagues,

Forensic sciences have seen remarkable development in recent years thanks to the advancement of numerous new diagnostic technologies in forensic pathology. We are witnessing the development of new fields such as forensic proteomics consisting in the identification of proteins and their characterization with respect to structure, function, activity, quantity and molecular interactions in the forensic field. In this direction, various studies have, for example, explored the role of the identification of new protein biomarkers analyzed on post-mortem biological samples in order to provide new scientific evidence with respect to various questions of forensic interest including the post-mortem interval (PMI) or the cause of death. The purpose of this Special Issue is to demonstrate the role that the study of proteins and in general that forensic laboratory investigations on cadavers can have in post-mortem diagnostics and in forensic sciences. This Special Issue is supervised by Prof. Dr. Isabella Aquila and assisted by our Topical Advisory Panel Member Dr. Matteo Antonio Sacco. To this end, contributions on the following topics are welcome:

  • forensic proteomics;
  • proteins;
  • post-mortem interval;
  • molecular interactions;
  • forensic biology;
  • forensic biochemistry;
  • forensic laboratory;
  • forensic investigations.

Prof. Dr. Isabella Aquila
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • proteomics
  • proteins
  • forensic biology
  • post mortem interval
  • forensic biochemistry

Published Papers (2 papers)

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Editorial

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Editorial
Proteomics: A New Research Frontier in Forensic Pathology
Int. J. Mol. Sci. 2023, 24(13), 10735; https://doi.org/10.3390/ijms241310735 - 27 Jun 2023
Viewed by 560
Abstract
Proteomics, the study of proteins and their functions, has revolutionized the field of forensic science by providing a powerful approach to identify and characterize proteins for various aims [...] Full article

Review

Jump to: Editorial

Review
Exploring the Potential of Proteome Analysis as a Promising Tool for Evaluation of Sudden Cardiac Death (SCD) in Forensic Settings: A Literature Review
Int. J. Mol. Sci. 2023, 24(18), 14351; https://doi.org/10.3390/ijms241814351 - 20 Sep 2023
Viewed by 198
Abstract
Sudden cardiac death (SCD) represents a global emergency, with a high number of cases affecting all age groups every year. The prevention of these fatal events requires an accurate knowledge of etiology and pathogenesis, which can vary. Autopsy is an indispensable tool in [...] Read more.
Sudden cardiac death (SCD) represents a global emergency, with a high number of cases affecting all age groups every year. The prevention of these fatal events requires an accurate knowledge of etiology and pathogenesis, which can vary. Autopsy is an indispensable tool in cases of SCD for diagnostic purposes, as well as for judicial and preventive purposes for family members. Despite the completion of all routine post-mortem investigations, it is often complicated for the forensic pathologist to define the triggering cause of these events. The study of the proteome is proving to be extremely promising in the field of human cardiovascular disease. This paper aims to offer a literature review on the study of the proteome in post-mortem cadaveric biological samples obtained from SCD cases. The aim of this work is to outline the state of the art of the scientific advances that protein analysis can offer in the diagnosis of SCD and the limits that various studies have traced up to now. In conclusion, the work defines the future perspectives of this field in SCD, suggesting strategies to overcome the reported limits and improve the diagnostics of these events. Full article
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