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Advances in Cancer Chemoprevention and Therapeutics
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Advances in Cancer Chemoprevention and Therapeutics

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 3043

Special Issue Editor

Prof. Dr. Shun-Fa Yang

E-Mail Website
Guest Editor
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
Interests: cancer prevention; cancer biomarker; oral cancer; cancer metastasis; polymorphism; tumor microenvironment; matrix metalloproteinase
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Despite current advances in surgery and other treatment options, the fatality of some cancers has remained mostly unchanged. Studies have shown that phytochemicals have the capability to prevent carcinogenesis. Therefore, new active compounds responsible for the anti-cancer characteristics of dietary plants, and original active compounds exert novel function on anti-carcinogenesis, are important issues in cancer investigation. We invite the researchers to contribute original and review articles regarding the relationship between phytochemicals and cancers, including the discovery of novel anti-cancer phytochemicals and the novel signalling pathways, and signalling molecules of phytochemicals on cancer treatment. We are pleased to invite you to our Special Issue on “Advances in Cancer Chemoprevention and Therapeutics”. We look forward to receiving your contributions.

Prof. Dr. Shun-Fa Yang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • phytochemicals
  • cancer
  • chemoprevention
  • metastasis
  • apoptosis
  • therapeutic target
  • biomarkers

Published Papers (1 paper)

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Review

45 pages, 889 KiB  
Review
Colorectal Cancer Chemoprevention: A Dream Coming True?
by Martina Lepore Signorile, Valentina Grossi, Candida Fasano and Cristiano Simone
Int. J. Mol. Sci. 2023, 24(8), 7597; https://doi.org/10.3390/ijms24087597 - 20 Apr 2023
Cited by 4 | Viewed by 2703
Abstract
Colorectal cancer (CRC) is one of the deadliest forms of cancer worldwide. CRC development occurs mainly through the adenoma-carcinoma sequence, which can last decades, giving the opportunity for primary prevention and early detection. CRC prevention involves different approaches, ranging from fecal occult blood [...] Read more.
Colorectal cancer (CRC) is one of the deadliest forms of cancer worldwide. CRC development occurs mainly through the adenoma-carcinoma sequence, which can last decades, giving the opportunity for primary prevention and early detection. CRC prevention involves different approaches, ranging from fecal occult blood testing and colonoscopy screening to chemoprevention. In this review, we discuss the main findings gathered in the field of CRC chemoprevention, focusing on different target populations and on various precancerous lesions that can be used as efficacy evaluation endpoints for chemoprevention. The ideal chemopreventive agent should be well tolerated and easy to administer, with low side effects. Moreover, it should be readily available at a low cost. These properties are crucial because these compounds are meant to be used for a long time in populations with different CRC risk profiles. Several agents have been investigated so far, some of which are currently used in clinical practice. However, further investigation is needed to devise a comprehensive and effective chemoprevention strategy for CRC. Full article
(This article belongs to the Special Issue Advances in Cancer Chemoprevention and Therapeutics)
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