Genetics and Epigenetics of Cardiometabolic Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 20 May 2024 | Viewed by 2110
Special Issue Editor
Interests: single-nucleotide polymorphisms; genetic risk score; Roma; type 2 diabetes; high-density lipoprotein cholesterol; haplotype; cardiometabolic risk factors; metabolic syndrome; genetics; polygenic risk score; obesity; genetic susceptibility; HDL subfraction profile; insulin resistance; dyslipidemia
Special Issue Information
Dear Colleagues,
Cardiometabolic diseases (CMDs) are currently the leading cause of death worldwide and therefore the most serious health challenge in both developing and developed countries. CMDs are the result of a combination of lifestyle/environmental and genetic factors that often lead to obesity and associated insulin resistance and hyperlipidaemia, type 2 diabetes, non-alcoholic fatty liver disease, and rare metabolic disorders, all of which increase the risk of cardiovascular disease, including myocardial infarction, stroke, and heart failure.
In recent decades, developments in bioinformatics and pharmacology have provided great insight into the genetic background of CMDs. Genome-wide association studies have improved our understanding of CMDs and identified polymorphisms (such as single-nucleotide polymorphisms) that contribute to their development. Pharmacogenetics has shown that individuals with different pharmacogenetics respond differently to the same drug.
The aim of this Special Issue of the International Journal of Molecular Sciences, titled "Genetics and Epigenetics of Cardiometabolic Diseases", is to summarise recent advances in genetics/epigenetics and related research into the underlying causes of cardiometabolic diseases and to identify important issues for the future. We welcome original research and reviews summarising recent advances in the screening, diagnosis, or treatment of cardiometabolic diseases with a genetic component.
Dr. Péter Pikó
Guest Editor
Manuscript Submission Information
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Keywords
- obesity
- insulin resistance
- diabetes mellitus
- cardiovascular diseases
- metabolic syndrome
- non-alcoholic fatty liver disease
- dyslipidaemia
- coronary artery disease
- chronic kidney disease
- hypertension