Special Issue "Aptamers: Functional and Structural Studies"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 31 October 2023 | Viewed by 1222
Special Issue Editor
Interests: aptamers; modified oligonucleotides; G-quadruplexes; triplexes; i-motif; RNA; DNA; therapeutic oligonucleotides; diagnostics; theranostics; cancer treatment; nucleic acids thermodynamics
Special Issue Information
Dear Colleagues,
Aptamers are short fragments of nucleic acids that form specific, unique, and stable structures that bind target molecules with high affinity and selectivity. They are often named chemical antibodies, but in contrast to antibodies, they are characterized by the ease of their synthesis and storage, low production costs and minor batch-to-batch variability, negligible immunogenicity, a broad repertoire of targets, and the feasibility of chemical modifications. Most aptamers are developed in vitro using a SELEX procedure; however, some naturally occurring aptamers were also sparsely found to be the elements of cell machinery. Due to the unquestionable benefits that they provide, aptamers can be applied as therapeutics, biosensors, or diagnostics in diverse areas including modern biotechnology, molecular biology, and biomedicine.
This Special Issue aims to cover fundamental aspects of aptamers, changing trends in aptamer technology, and their innovative applications in biotechnological and biomedical fields. We welcome submissions of research articles and reviews.
Dr. Anna Pasternak
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aptamers
- RNA
- DNA
- therapeutics
- diagnostics
- theranostics
- biosensors
