Advances in Cancer-Related Transcriptome and Genome Analyses
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (30 March 2024) | Viewed by 2213
Special Issue Editor
Interests: bioinformatics; RNA-seq; DNA-seq; scRNA-seq; transcriptomics; cancer; blood diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The advent of high-throughput sequencing technologies opened a new era in molecular medicine and cancer research, allowing the genome-wide study of the molecular characteristics of tumours at the nucleotide level. As a more recent technology, single-cell sequencing allows an even higher resolution for dissecting the tumour environment at the cellular scale, while long-read sequencing improves genome assembly and the detection of transcript isoforms and structural variants.
DNA-seq and RNA-seq experiments generate massive amounts of data, which require the application of advanced interdisciplinary techniques, including bioinformatics, biostatistics, and artificial intelligence, to extract meaningful information. The molecular complexity of tumours, which requires the combination of multiple levels of information, and the difficulties of cancer studies (e.g., scarcity of samples, cost, and time limitations) make transcriptome and genome analysis even more challenging in cancer research.
In this Special Issue, we welcome submissions of original research articles, reviews, short communications, and perspectives on cancer-related transcriptome and genome analyses, with a focus on the analysis of novel or existing cancer omics data sets bringing new knowledge on molecular mechanisms and aberrancies driving tumour biogenesis and progression. We also accept studies presenting newly developed computational methods, software and resources for cancer research or the improvement of existing ones.
Dr. Enrico Gaffo
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- genomics
- transcriptomics
- omic data integration
- computational analysis
- RNA-seq
- DNA-seq
- scRNA-seq
- long-read sequencing
