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Gels
Special Issues
Bio-Based Hydrogels: Design, Synthesis and Applications
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Bio-Based Hydrogels: Design, Synthesis and Applications

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Chemistry and Physics".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 510

Special Issue Editors

Dr. Guogao Zhang

E-Mail Website
Guest Editor
John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA
Interests: hydrogels; soft materials and mechanics; fracture and fatigue; polymer science
Dr. Gibson S. Nyanhongo

E-Mail Website
Guest Editor
Department of Biotechnology and Food Technology, Faculty of Science, Corner Siemert and Louisa, Doornfontein 2028, John Orr Building, University of Johannesburg, Johannesburg, South Africa
Interests: polymer chemistry; hydrogels; biomaterial engineering; biocatalytic synthesis; bioeconomy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bio-based hydrogels are a type of smart material that can swell and absorb large amounts of water or biological fluids. They are composed of natural polymers, such as cellulose, chitosan, alginate, and gelatin, which have great potential in developing advanced biomedical applications. Bio-based hydrogels have gained significant attention in recent years due to their biocompatibility, biodegradability, and non-toxic nature. In addition to their potential benefits, the development of bio-based hydrogels also presents significant challenges, including the optimization of their mechanical properties, stability, and controllable release kinetics. This Special Issue includes articles that cover various aspects of bio-based hydrogels, such as their synthesis, characterization, and properties, as well as their applications in drug delivery, tissue engineering, wound healing, and environmental, agricultural, and industrial applications. The articles also discuss the challenges and opportunities in the field of bio-based hydrogels and highlight the potential of these materials in developing innovative and sustainable solutions for biomedical applications.

Dr. Guogao Zhang
Dr. Gibson S. Nyanhongo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bio-based hydrogels
  • biomaterials
  • natural polymers
  • biocompatibility
  • biodegradability
  • drug delivery
  • tissue engineering
  • wound healing

Published Papers (1 paper)

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Research

17 pages, 3482 KiB  
Article
Non-Covalent Cross-Linking Hydrogel: A New Method for Visceral Hemostasis
by Chenyu Zhao, Han Wang, Xue Sun, Ying Liu, Jingjing Chen, Jiaqi Li, Fanshan Qiu and Qianqian Han
Gels 2024, 10(5), 326; https://doi.org/10.3390/gels10050326 - 10 May 2024
Viewed by 229
Abstract
Excessive blood loss could lead to pathological conditions such as tissue necrosis, organ failure, and death. The limitations of recently developed hemostatic approaches, such as their low mechanical strength, inadequate wet tissue adhesion, and weak hemostatic activity, pose challenges for their application in [...] Read more.
Excessive blood loss could lead to pathological conditions such as tissue necrosis, organ failure, and death. The limitations of recently developed hemostatic approaches, such as their low mechanical strength, inadequate wet tissue adhesion, and weak hemostatic activity, pose challenges for their application in controlling visceral bleeding. In this study, a novel hydrogel (CT) made of collagen and tannic acid (TA) was proposed. By altering the proportions between the two materials, the mechanical properties, adhesion, and coagulation ability were evaluated. Compared to commercial hydrogels, this hydrogel has shown reduced blood loss and shorter hemostatic time in rat hepatic and cardiac bleeding models. This was explained by the hydrogel’s natural hemostatic properties and the significant benefits of wound closure in a moist environment. Better biodegradability was achieved through the non-covalent connection between tannic acid and collagen, allowing for hemostasis without hindering subsequent tissue repair. Therefore, this hydrogel is a new method for visceral hemostasis that offers significant advantages in treating acute wounds and controlling major bleeding. And the production method is simple and efficient, which facilitates its translation to clinical applications. Full article
(This article belongs to the Special Issue Bio-Based Hydrogels: Design, Synthesis and Applications)
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