Bio-Based Hydrogels: Design, Synthesis and Applications

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Chemistry and Physics".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 856

Special Issue Editors


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Guest Editor
John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA
Interests: hydrogels; soft materials and mechanics; fracture and fatigue; polymer science

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Guest Editor
Department of Biotechnology and Food Technology, Faculty of Science, Corner Siemert and Louisa, Doornfontein 2028, John Orr Building, University of Johannesburg, Johannesburg, South Africa
Interests: polymer chemistry; hydrogels; biomaterial engineering; biocatalytic synthesis; bioeconomy
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Special Issue Information

Dear Colleagues,

Bio-based hydrogels are a type of smart material that can swell and absorb large amounts of water or biological fluids. They are composed of natural polymers, such as cellulose, chitosan, alginate, and gelatin, which have great potential in developing advanced biomedical applications. Bio-based hydrogels have gained significant attention in recent years due to their biocompatibility, biodegradability, and non-toxic nature. In addition to their potential benefits, the development of bio-based hydrogels also presents significant challenges, including the optimization of their mechanical properties, stability, and controllable release kinetics. This Special Issue includes articles that cover various aspects of bio-based hydrogels, such as their synthesis, characterization, and properties, as well as their applications in drug delivery, tissue engineering, wound healing, and environmental, agricultural, and industrial applications. The articles also discuss the challenges and opportunities in the field of bio-based hydrogels and highlight the potential of these materials in developing innovative and sustainable solutions for biomedical applications.

Dr. Guogao Zhang
Dr. Gibson S. Nyanhongo
Guest Editors

Manuscript Submission Information

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Keywords

  • bio-based hydrogels
  • biomaterials
  • natural polymers
  • biocompatibility
  • biodegradability
  • drug delivery
  • tissue engineering
  • wound healing

Published Papers (1 paper)

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Research

17 pages, 3482 KiB  
Article
Non-Covalent Cross-Linking Hydrogel: A New Method for Visceral Hemostasis
by Chenyu Zhao, Han Wang, Xue Sun, Ying Liu, Jingjing Chen, Jiaqi Li, Fanshan Qiu and Qianqian Han
Gels 2024, 10(5), 326; https://doi.org/10.3390/gels10050326 - 10 May 2024
Viewed by 522
Abstract
Excessive blood loss could lead to pathological conditions such as tissue necrosis, organ failure, and death. The limitations of recently developed hemostatic approaches, such as their low mechanical strength, inadequate wet tissue adhesion, and weak hemostatic activity, pose challenges for their application in [...] Read more.
Excessive blood loss could lead to pathological conditions such as tissue necrosis, organ failure, and death. The limitations of recently developed hemostatic approaches, such as their low mechanical strength, inadequate wet tissue adhesion, and weak hemostatic activity, pose challenges for their application in controlling visceral bleeding. In this study, a novel hydrogel (CT) made of collagen and tannic acid (TA) was proposed. By altering the proportions between the two materials, the mechanical properties, adhesion, and coagulation ability were evaluated. Compared to commercial hydrogels, this hydrogel has shown reduced blood loss and shorter hemostatic time in rat hepatic and cardiac bleeding models. This was explained by the hydrogel’s natural hemostatic properties and the significant benefits of wound closure in a moist environment. Better biodegradability was achieved through the non-covalent connection between tannic acid and collagen, allowing for hemostasis without hindering subsequent tissue repair. Therefore, this hydrogel is a new method for visceral hemostasis that offers significant advantages in treating acute wounds and controlling major bleeding. And the production method is simple and efficient, which facilitates its translation to clinical applications. Full article
(This article belongs to the Special Issue Bio-Based Hydrogels: Design, Synthesis and Applications)
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