Gel-Based Drug Delivery Systems for Cancer Treatment
A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 17979
Special Issue Editors
Interests: nanomedicine; hydrogel; tumor hyperthermia
Interests: hydrogel; drug release
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hydrogels have been widely utilized for drug delivery to various diseases, especially for cancer, in which the unique features (e.g., ROS, GSH, hypoxia and acidic pH) are beneficial for the design of drug delivery systems. Numerous new drug delivery strategies based on functional hydrogels have been proposed in recent years. For example, injectable hydrogels can be implanted into tumor tissue in a minimally invasive manner to maintain a high drug concentration and reduce systemic toxic side effects. A pH-sensitive hydrogel maintains its stable state at physiological pH, but is labile at mildly acidic pH in tumor microenvironments, which can be exploited for enhanced cancer therapy. Hydrogel vaccines show great potential in cancer immunotherapy by causing a potent and durable antitumor response. The development of hydrogels with desirable functionalities has a promising future in intelligent therapy of cancer.
This Special Issue intends to highlight the topics related to the use of functional gels in assisting cancer treatment of therapeutic agents, delivering therapy-related components with different modes of administration. Additionally, gels used for stimuli-responsive drug release and for facilitating chemo-dynamic therapy, immunotherapy and thermotherapy will also be featured.
Scope:
- Functional hydrogel
1.1 Stimuli-responsive hydrogel
(Endogenous stimulus: pH, GSH, ROS, MMP2, etc.; exogenous stimuli: light, thermo, etc.)
1.2 Bioinspired hydrogel
- Smart delivery hydrogel
2.1 Injectable hydrogel (minimally invasive administration)
2.2 Nanogel (systemic administration)
- Hydrogel for combination therapy
3.1 Chemo-dynamic therapy
3.2 Immunotherapy
3.3 Thermotherapy
- Wound dressing or wound healing
Dr. Haoan Wu
Prof. Dr. Xingchun Gao
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
1. Title: Docosahexaenoic acid improves the antineoplastic effect of a hyaluronic acid and folic acid-based hydrogel containing cisplatin in human ovarian cancer cells in vitro
Author: Dr. Roberta Cassano