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Dentistry Journal
Special Issues
Photobiomodulation and Its Application in Dentistry
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Photobiomodulation and Its Application in Dentistry

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Lasers in Dentistry".

Deadline for manuscript submissions: 1 November 2024 | Viewed by 7525
Please submit your paper and select the Journal "Dentistry Journal" and the Special Issue "Photobiomodulation and Its Application in Dentistry" via: https://susy.mdpi.com/user/manuscripts/upload?journal=dentistry Please contact the Managing Editor Ms. Adele Min (adele.min@mdpi.com) before submitting.

Special Issue Editors

Prof. Dr. Alessandro Del Vecchio

E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Science, Sapienza University of Rome, 00161 Rome, Italy
Interests: oral pathology and medicine; clinical dentistry; laser dentistry; photobiomodulation
Dr. Francisco José Gomez Garcia

E-Mail Website
Guest Editor
Department of Oral Medecine, University of Murcia, 3008 Murcia, Spain
Interests: oral cancer; periodontal disease; bone density
Dr. Luís Monteiro

E-Mail Website
Guest Editor
1. Department of Oral Medicine and Oral Surgery, University Institute of Health Sciences (IUCS-CESPU), 4585-116 Gandra, Portugal
2. UNIPRO—Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS-CESPU), Gandra, Portugal
Interests: oral cancer; oral leukoplakia; prognostic markers; laser; immunohistochemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

About 60 years have passed since the first studies about the Photobiomodulation (PBM) were enounced; however, the diffusion of this biological way of treatment is still limited to few researchers and to even less clinical practitioners. Recent studies have shown both in vitro and in vivo the potentialities of therapeutic lights and their beneficial effects in the treatment of many pathologies even though many questions remain controversial, especially about dosages and therapeutic protocols.

The PBM has anti-inflammatory and analgesic action, reducing local edema, and improving the peripheral microcirculation; it stimulates the proliferation of many cell types as fibroblasts, osteoblasts, neurons and collagen fibers, improving the tissue healing processes; PBM induces the vitality and the effectiveness of the immunologic processes too, enhancing the defensive reactions of the organism.

All these properties can be easily applied in the daily dental practice determining a considerable improvement of the results of many common treatments in a biological way, without any adverse side effect.

This Special Issue is interested in all the aspects of dental and medical specialties dealing with this topic. Basic research about light biological effects, literature reviews concerning dosages and outcomes, clinical reports about the treatment of many pathological conditions and studies about the future perspectives of PBM are of interest, in the main aim of enlarging the diffusion of this therapeutic method among dental and medical practitioners.

Prof. Dr. Alessandro Del Vecchio
Dr. Francisco José Gomez Garcia
Dr. Luís Monteiro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • photobiomodulation
  • laser therapy
  • LLLT
  • PBM
  • soft laser
  • medical laser
  • LILT
  • Low Intensity Laser
  • wound healing
  • laser analgesia
  • oral pain management

Published Papers (3 papers)

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Research

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13 pages, 2777 KiB  
Article
Effects of Semiconductor Laser Irradiation on Differentiation of Human Dental Pulp Stem Cells in Co-Culture with Dentin
by Masafumi Yarita, Kayoko Kitajima, Takao Morita and Koichi Shinkai
Dent. J. 2024, 12(3), 67; https://doi.org/10.3390/dj12030067 - 05 Mar 2024
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Abstract
This study aimed to determine the effect of photobiomodulation therapy induced by semiconductor laser irradiation on human dental pulp stem cell (hDPSC) proliferation and their differentiation into odontoblast-like cells (OLCs). The effects of various semiconductor laser irradiation conditions on hDPSCs were examined. Three [...] Read more.
This study aimed to determine the effect of photobiomodulation therapy induced by semiconductor laser irradiation on human dental pulp stem cell (hDPSC) proliferation and their differentiation into odontoblast-like cells (OLCs). The effects of various semiconductor laser irradiation conditions on hDPSCs were examined. Three groups were evaluated: a single laser irradiation at 6 h post-seeding, multiple laser irradiations up to four times every 4 days after the first dose, and a control with no laser irradiation. The cells were irradiated at 10, 30, and 150 mW using a semiconductor laser. The effect of laser irradiation on hDPSC differentiation into OLCs was also determined. Four groups were evaluated, including co-culture using basic medium and dentin discs, simple culture using OLC differentiation-inducing medium, co-culture using OLC differentiation-inducing medium and dentin discs, and control culture with basic medium. The expression of the nestin, ALP, DSPP, and DMP-1 genes was measured using real-time PCR. The multiple irradiation group irradiated at 30 mW exhibited significantly more cell proliferation than the control. The expression of nestin associated with differentiation into OLCs during each culture period tended to be lower, whereas DSPP and ALP expression was higher compared with that of the control. Multiple laser irradiations at a low power of 30 mW induced significant hDPSC proliferation and might induce differentiation into OLCs. Full article
(This article belongs to the Special Issue Photobiomodulation and Its Application in Dentistry)
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Review

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12 pages, 415 KiB  
Review
Comparison of Lasers and Desensitizing Agents in Dentinal Hypersensitivity Therapy
by Francesca Cattoni, Lucrezia Ferrante, Sara Mandile, Giulia Tetè, Elisabetta Maria Polizzi and Giorgio Gastaldi
Dent. J. 2023, 11(3), 63; https://doi.org/10.3390/dj11030063 - 27 Feb 2023
Cited by 8 | Viewed by 3782
Abstract
The main objective of this review is to verify the validity of laser therapy in the treatment of dentin hypersensitivity, an extremely common problem in patients, with Nd: YAG lasers or high- and/or low-power diode lasers to obtain a definitive protocol for the [...] Read more.
The main objective of this review is to verify the validity of laser therapy in the treatment of dentin hypersensitivity, an extremely common problem in patients, with Nd: YAG lasers or high- and/or low-power diode lasers to obtain a definitive protocol for the treatment of hypersensitivity, given the multiplicity of laser treatments proposed by the numerous authors evaluated. The authors performed an electronic search on PubMed, favouring it as a search engine. Lasers represent a means of treating dentin hypersensitivity, used alone and/or in conjunction with specific products for the treatment of such a pathology. The selected articles that examined diode lasers were divided according to the wattage (w) used: low-level laser therapy protocols, i.e., those using a wattage of less than 1 W, and high-level laser therapy protocols, i.e., those using a wattage of 1 W or more. Regarding the Nd: YAG laser, it was not necessary to subdivide the studies in this way, as they used a wattage of 1 W or more. A total of 21 articles were included in the final selection. Laser therapy was found to be effective in the treatment of dentin hypersensitivity. However, the level of effectiveness depends on the laser used. The results obtained from this review show that both the Nd: YAG laser and the diode laser (high and low power) are effective in the treatment of dentin hypersensitivity. However, the high-power laser appears to be more effective in combination with fluoride varnish and the Nd: YAG laser achieved greater long-term benefits than the diode laser. Full article
(This article belongs to the Special Issue Photobiomodulation and Its Application in Dentistry)
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Other

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10 pages, 571 KiB  
Systematic Review
Effect of Photobiomodulation on Atrophic–Erosive Clinical Forms of Oral Lichen Planus: A Systematic Review
by Juan Antonio Ruiz Roca, Pía López Jornet, Francisco José Gómez García and Paula Marcos Aroca
Dent. J. 2022, 10(12), 221; https://doi.org/10.3390/dj10120221 - 27 Nov 2022
Cited by 5 | Viewed by 1894
Abstract
Introduction. Oral lichen planus is a chronic autoimmune inflammatory disease of unknown origin, characterized by various clinical forms of which the atrophic–erosive causes patients the greatest symptomatology. For this reason, there are different treatments that improve the associated signs and symptoms. One of [...] Read more.
Introduction. Oral lichen planus is a chronic autoimmune inflammatory disease of unknown origin, characterized by various clinical forms of which the atrophic–erosive causes patients the greatest symptomatology. For this reason, there are different treatments that improve the associated signs and symptoms. One of these therapies is photobiomodulation (PBM), which, although new, has a high level of acceptance in dentistry based on evidence. However, there are inconsistent results in its application against lichen planus. The aim of this review was to evaluate the effect of photobiomodulation and its effectiveness as a therapeutic alternative for atrophic–erosive lesions. Material and methods. The databases PubMed, Google Scholar and Cochrane Library were searched to identify studies investigating the photobiomodulation treatment in atrophic–erosive lesions of oral lichen planus. A total of 294 articles were identified, published between 2017 and 2022, and then evaluated; 7 articles that met all the inclusion criteria were included in this study. Results. The type of laser light source used in PBM was the diode laser (four cases), the Nd–YAG laser at the same wavelength of 1064 nm (two cases) and the He–Ne laser (one case). The minimum and maximum wavelengths used were 630 nm and 1064 nm, respectively. Most studies used lesions treated with topical corticosteroids as a control group. The follow-up times of the studies were highly variable. Conclusions. Photobiomodulation is a treatment that competently combats oral lichen planus lesions by improving signs and symptoms, with no known adverse reactions so far, which makes it more beneficial compared to more conventional therapies, such as corticosteroids, for which side effects have been found. Full article
(This article belongs to the Special Issue Photobiomodulation and Its Application in Dentistry)
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