Natural Products in Neurodegenerative Diseases: Current Trends and Future Perspectives
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 1876
Special Issue Editors
Interests: metabolic studies; protein–ligand interactions; protein aggregation processes in AD; metabolomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The continuing demographic transition toward an aging society is leading to the growing prevalence of chronic age-related diseases. This is extremely important due to the lack of effective treatment and associated immense socioeconomic burden on all industrialized countries. Neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) are persistent progressive diseases associated with an abnormal accumulation and aggregation of disease-specific proteins and peptides. Such changes have been linked to a noticeable activation of immune responses, increased levels of oxidative stress and neuronal cell death. Even though there has been tremendous knowledge growth into the disease mechanisms of neurodegenerative disorders, there is a great need for developing effective disease-modifying agents. Medicinal plants have been used for their “anti-aging” and cognitive enhancing properties. In view of a suggested mechanistic link between oxidative stress, inflammation and neurodegeneration, plant-derived neuroprotective compounds and dietary antioxidants may offer a promising therapeutic route for modifying the progression or protecting against the risk of neurodegenerative diseases.
Prof. Dr. Anthony Tsarbopoulos
Dr. Nikolaos Kokras
Guest Editors
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Keywords
- bioactive compounds
- protein aggregation processes in AD
- cognitive, anxiolytic and antidepressant effects
