Protein Misfolding Diseases: From Experimental Approaches to Therapeutic Opportunities
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 2389
Special Issue Editors
Interests: amyloid protein; neurodegenerative diseases; type 2 diabetes; biophysics
Interests: neurodegeneration; Parkinson’s disease; Alzheimer’s disease; protein aggregation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Protein misfolding and amyloid formation are the pathognomonic modalities behind the most globally prevalent neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. With the worldwide prevalence of dementia, a common pathological consequence of these neurodegenerative diseases that is expected to almost triple in less than thirty years, they pose significant challenges to healthcare systems worldwide. Strikingly, protein aggregation seems to also be an important hallmark in other highly prevalent diseases, such as cancer and diabetes, suggesting that shared mechanisms may be involved.
This Special Issue welcomes review articles and original reports that will improve our understanding of the mechanisms involved in protein misfolding diseases. A deeper understanding of these mechanisms, and the cross-fertilization between different fields will create opportunities for developing novel diagnostics and treatment modalities for many devastating diseases.
Dr. Ali Chaari
Prof. Dr. Tiago Fleming Outeiro
Guest Editors
Manuscript Submission Information
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Keywords
- protein aggregation
- amyloid
- neurodegenerative diseases
- cancer
- diabetes
