Fluorescent Materials for Sensing, Bioimaging, Disease Diagnosis, and Therapeutics

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Microenvironment".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 3343

Special Issue Editors


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Guest Editor
Department of Chemistry, Pohang University of Science and Technology (POSTECH), Gyeongbuk 37673, Korea
Interests: molecular probes; bioimaging; disease diagnosis; therapeutics; fluorescence chemistry

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Guest Editor
Department of Chemistry, University of California, Riverside, CA 92521, USA
Interests: DNA modifications; epigenetics; nucleic acid chemistry; DNA sequencing; DNA probe; cancer
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Department of Ophthalmology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Interests: biophysics; lens protein glycation; protein stability; folding; aggregation; spectroscopy; microscopy

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Guest Editor
Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India
Interests: therapeutics; theranostics
Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane 4072, Australia
Interests: analytical chemistry; biosensing and bioimaging; photochemistry; nanotechnology; nano-bio interface chemistry; nanobiosensors; theranostic nanomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Since the discovery of the fluorescence-based sensing technique in the mid-1980s, it has expanded into several advanced fields, such as bioimaging, disease diagnosis, therapeutics, surgery, etc. In recent years, fluorescence-based techniques have become an indispensable tool to investigate biological systems due to their simplicity, cheap mode of operation, higher resolution, and noninvasiveness.

The objective of this Special Issue is to sketch an overview of recent trends in fluorescence-based sensing methods in biological applications. This issue will cover a broad field, starting from the development of fluorescent materials to their application in bioimaging, designing bioanalyte-selective probes and fluorescent tags for studying chemical biology, also monitoring inter/intracellular dynamics of analytes for disease diagnosis, therapeutics, and surgery. High-quality research articles demonstrating original scientific results and review articles summarizing outstanding features of this field are encouraged for submission to this Special Issue.

Potential topics are summarized below:

  • Chemiluminescence
  • One photon/multiphoton absorbing fluorescent materials
  • Fluorescence-based sensing
  • Fluorescent materials for organelle labeling
  • Fluorescent tags in exploring chemical biology
  • Fluorescent probes in disease diagnosis
  • Fluorescence-assisted monitoring of drug delivery
  • Fluorophores in photodynamic/photothermal therapy
  • Fluorescence imaging-guided surgery

Dr. Sourav Sarkar
Dr. Chaoxing Liu
Dr. Sudipta Panja
Dr. Avijit Jana
Dr. Run Zhang
Guest Editors

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Keywords

  • fluorescence
  • sensing
  • imaging
  • diagnosis
  • therapeutics
  • surgery
  • chemical biology

Published Papers (1 paper)

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Research

7 pages, 1958 KiB  
Communication
Human-T-Cell-Selective Fluorescent Probe
by Min Gao and Young-Tae Chang
Cells 2022, 11(18), 2836; https://doi.org/10.3390/cells11182836 - 11 Sep 2022
Cited by 1 | Viewed by 2323
Abstract
The identification of T and B lymphocytes has relied on using antibodies against different biomarkers as the gold standard. Emerging small molecule-based fluorescent probes have the potential to replace antibodies. Herein, we report the first human-T-cell-selective fluorescent probe, Mito thermo yellow (MTY), achieving [...] Read more.
The identification of T and B lymphocytes has relied on using antibodies against different biomarkers as the gold standard. Emerging small molecule-based fluorescent probes have the potential to replace antibodies. Herein, we report the first human-T-cell-selective fluorescent probe, Mito thermo yellow (MTY), achieving the live T cells’ distinction from B cells, which was previously impossible without the help of antibodies. The unexpected cell selectivity of MTY is attributed to the higher mitochondria mass and membrane potential of T cells over B cells. This study enriches the toolbox for live cell distinction from complex cell communities. Full article
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