Understanding the Extracellular Vesicles (EVs)-Mediated Horizontal Transfer of Non-coding RNAs
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 30 June 2024 | Viewed by 1907
Special Issue Editors
Interests: non-coding RNAs; cancer; hypoxia; extracellular vesicles; cell-cell communication
Special Issues, Collections and Topics in MDPI journals
Interests: EMT; tumor progression; non-coding RNAs; intercellular communication
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) differ in size, surface antigen, and origin; however, they have in common the ability to transport non-coding RNAs between cells. Among them, small RNA families are the most abundant; these include small nuclear RNAs, small nucleolar RNAs, ribosomal RNAs, transfer RNAs, and miRNAs. More recently, larger RNAs groups, including mitochondrial RNAs, Y RNA, vault RNA, piwi RNA, and long non-coding RNA, have also been found in EVs isolated from different cytotypes.
Today, a direct effect in receiving cells has been demonstrated only for some of these RNA families, whereas for the vast majority of them a functional role is only hypothesized. Equally still unclear are the strategies that cells adopt for selective loading into EVs of specific RNAs.
This Special Issue will collect original research articles and reviews, providing a picture of the current advances in this field to improve the understanding of the functional roles of EV-associated ncRNAs in physiopathology. We welcome papers from basic and clinical researchers, as well as in vitro and in vivo studies.
Dr. Alice Conigliaro
Dr. Carla Cicchini
Guest Editors
Manuscript Submission Information
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Keywords
- extracellular vesicles
- non-coding RNA
- horizontal transfer
- RNA loading
- RNA binding proteins
