CD38 in Basic Science: Reflecting on the Past to Move to the Future

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: closed (15 September 2023) | Viewed by 276

Special Issue Editors


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Guest Editor
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, 47014 Meldola, Italy
Interests: acute lymphoblastic leukemia; acute myeloid leukemia; myelodysplastic syndromes; multiple myeloma and MGUS; non-Hodgkin and Hodgkin lymphoma
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Guest Editor
Department of Medical Science, University of Turin and Fondazione Ricerca Molinette, 10123 Turin, Italy
Interests: antibody therapy; human myeloma; leukemia; IgG receptors; immune modulation
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Guest Editor
1. Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, USA
2. Division of Hematology & Oncology, Mayo Clinic, Jacksonville, FL 32224, USA
Interests: multiple myeloma; MGUS; chronic lymphocytic leukemia; waldenstrom macroglobulinemia; immunotherapy; cancer vaccines; antibody therapy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

More than three decades of research on CD38 and its role in human diseases has culminated in the recent development of agents that target CD38 for clinical applications. The formal approval and expanding use of anti-CD38 therapeutic antibodies have allowed them to become an important treatment option in the management of multiple myeloma. On the heels of this success, the efficacy of CD38-targeting agents is being actively investigated for patients with other hematologic malignancies, solid tumour cancers, and autoimmune disorders, as well as pathologies related to ageing, neurodegenerative disorders, neuropsychology, and cardiovascular disease.

With an abundance of scientific data being released on CD38 biology and the development of novel anti-CD38 therapies, our conference entitled, “CD38 in Basic Science and Clinical Practice: Reflecting on the Past to Move into the Future” is timely, and will bring together experts investigating the role of CD38 in cancer, ageing, autoimmunity, neurology and behaviour.  This important conference will foster much needed engagement between clinicians, basic-science researchers and pharmaceutical companies working on CD38. As anti-CD38 therapies are currently approved for use in patients with multiple myeloma, a major theme of the meeting will be on the optimal use of these agents and novel therapeutic strategies once patients stop responding to the targeted interference of CD38. The meeting is being organized by experts in the field (Drs. Cerchione, Paulus, and Malavasi) with the support of their respective academic institutes and patronage from various professional societies, pharmaceutical partners, and philanthropists.

This Special Issue aims to collect papers related to major topics of our conference, including Reviews, Original papers, Commentaries and Editorials.

Dr. Claudio Cerchione
Prof. Dr. Fabio Malavasi
Dr. Aneel Paulus
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • CD38
  • multiple myeloma
  • myeloma
  • MGUS
  • monoclonal antibodies
  • immunotherapy

Published Papers

There is no accepted submissions to this special issue at this moment.
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