Special Issue "DNA Biosensors for Highly Sensitive Detection"
Deadline for manuscript submissions: 30 November 2023 | Viewed by 5724
Interests: DNA biosensor; nucleic acid; polymer gel electrolyte; wearable/implantable flexible devices
Interests: biosensors; biomolecular responsive nanopores; bio-analytical chemistry
DNA has emerged as a versatile molecule for the development of biosensors due to its ability to recognize not only complementary nucleic acids but also metal ions, small molecules, proteins, and cells. Recently, different kinds of detection strategies have been reported, such as luminescence assays, fluorescence detection, colorimetric test, and surface plasmon resonance. However, many methods are time-consuming, expensive, and lack sensibility. Therefore, novel approaches in rapid, sensitive, and reliable detection should be urgently required, especially for early diagnosis. To date, owing to the high specificity and affinity, aptamer-based detection techniques have been widely developed. In almost all of the aptamer-based technologies, if without a signal amplification strategy, a one-to-one relationship between the aptamer and its correspondence target leads to low sensitivity and high error rate. Thus, various signal-amplification strategies have been widely explored, such as hybrid chain reaction, enzyme-assisted strand displacement reaction, and rolling circle amplification.
For this Special Issue, we invite you to share new signal amplification strategies of DNA-based biosensors for highly sensitive detection, in the form of original research or review articles, with a focus on their specific applications. We hope that by showcasing a range of different strategies from researchers around the world, the reader will gain an insight into the cutting-edge advancements that are taking place in this field, as well as develop an appreciation for the strengths (and limitations) of current technologies. We look forward to your contributions.
Prof. Dr. Jie Du
Prof. Dr. Fan Xia
Dr. Hui Zhang
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- real-time analysis
- sensor performance
- sensing mechanism
- signal amplification
- miniaturized systems
- highly sensitive detection