Enzyme Biosensors: Challenges and Future Perspectives

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 985

Special Issue Editors


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Guest Editor
Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory (NBRL), School of Science, RMIT University, GPO Box 2476, Melbourne, VIC 3000, Australia
Interests: biosensing; nanozymes; nanobiotechnology
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Guest Editor
Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Interests: enzymatic biosensors; optical substrates; hydrolases; cytochrome P450 enzymes; transferases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent advances in enzyme-based biosensors have propelled these devices to the forefront of analytical technologies, offering enhanced sensitivity, selectivity, and versatility in various applications. Enzyme-based biosensors leverage the catalytic activity of enzymes to convert biochemical reactions into measurable signals, providing valuable information about the presence and concentration of specific target analytes. However, the enzymes employed in these biosensors are intact and face challenges regarding stability, reproducibility, cost-effectiveness, biocompatibility, and biodegradation, underscoring the complexity and multi-faceted nature of biosensor development. Thus, researchers are actively seeking alternative approaches to address these challenges by exploring cutting-edge technologies, such as nanotechnology, advanced materials, microfluidics, and artificial intelligence, to promote the development of more robust, sensitive, and versatile analytical tools with broad applications in healthcare, environmental monitoring, and beyond.

Therefore, this Special Issue, “Enzyme Biosensors: Challenges and Future Perspectives”, encourages researchers and experts in the field to share their recent findings, insights, and methodologies to contribute to the collective knowledge base and drive further advancements in enzyme-based biosensors.

Dr. Pabudi Weerathunge
Prof. Dr. Guang-Bo Ge
Guest Editors

Manuscript Submission Information

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Keywords

  • enzymatic biosensors
  • artificial enzymes
  • enzyme-mimicking
  • nanozymes
  • nanosensors
  • point-of-care biosensors
  • electrochemical enzyme biosensors
  • optical enzyme biosensors
  • food safety biosensors
  • environmental biosensors

Published Papers (1 paper)

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Review

23 pages, 5990 KiB  
Review
Research Progress on the Application of Covalent Organic Framework Nanozymes in Analytical Chemistry
by Dongmei Yao, Ling Xia and Gongke Li
Biosensors 2024, 14(4), 163; https://doi.org/10.3390/bios14040163 - 29 Mar 2024
Viewed by 748
Abstract
Covalent organic frameworks (COFs) are porous crystals that have high designability and great potential in designing, encapsulating, and immobilizing nanozymes. COF nanozymes have also attracted extensive attention in analyte sensing and detection because of their abundant active sites, high enzyme-carrying capacity, and significantly [...] Read more.
Covalent organic frameworks (COFs) are porous crystals that have high designability and great potential in designing, encapsulating, and immobilizing nanozymes. COF nanozymes have also attracted extensive attention in analyte sensing and detection because of their abundant active sites, high enzyme-carrying capacity, and significantly improved stability. In this paper, we classify COF nanozymes into three types and review their characteristics and advantages. Then, the synthesis methods of these COF nanozymes are introduced, and their performances are compared in a list. Finally, the applications of COF nanozymes in environmental analysis, food analysis, medicine analysis, disease diagnosis, and treatment are reviewed. Furthermore, we also discuss the application prospects of COF nanozymes and the challenges they face. Full article
(This article belongs to the Special Issue Enzyme Biosensors: Challenges and Future Perspectives)
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