Immunometabolic Determinants of Gut–Liver Axis Health
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 60
Special Issue Editor
Interests: immunonutrition; macrophages; trained immunity; gut-liver axis; microbiota
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The bidirectional relationship between environmental conditions in the intestinal tract and liver function is undoubted and widely accepted. The interaction of stimuli affecting the gut microbiota and intestinal immune system are critical determinants of liver function. The composition of the microbiota seems to be subjected and conditioned to the maturation, orientation, and magnitude of the innate and adaptive immune responses. However, it is the ecometabolic conditions that are presented as key effectors in the function and direction of the immune response(s). These interactions determine the 'entero-hepatic' axis, this being the basis of various influences on the functions of other internal organs. A clear example of this is the impact of the entire hepatic axis on the function of the central nervous system, as well as the lungs and kidneys. From a global point of view, the pathologies associated with imbalances in the functions and immunometabolic conditions of these organs share bases that present their molecular origin in the emerging signaling in the intestinal context. This complex network of interactions in the 'entero-hepatic' axis represents an important challenge for the biomedical sector. Thus, it must face various aspects that are extremely involved in the development of pathologies with an enormous impact on our society. A critical view of this area of research reveals the existence of numerous unanswered questions, as well as the need for a multidisciplinary approach to support the translation of biomedical studies into effective precision medicines in health promotion.
Dr. Jose Moisés Laparra
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut microbiota
- 'entero-hepatic' axis
- gut–liver axis
- immunometabolism
