Materials for Biomedical Engineering and Regenerative Medicine

Dear Colleagues,

In the past two decades, various materials (such as polymers, hydrogels, metals, ceramics, composites, nanomaterials, etc.) have been engineered and widely used to augment tissue function, to replace damage organs, to treat diseases or injuries, and for recapitulating complex microenvironments for Bio-MEMS applications or organ/tissue-mimicking phantoms to address the current limitations with donor organs and problems with donor site morbidity. Today, more than ever we have an advanced toolbox of synthetic and processing techniques (i.e., electrospinning, 3D printing, bioprinting) to rationally design, create, and process materials with specific and tunable properties in mind. These advancements go hand in hand with the integration of theory with experiments and cutting-edge fabrication techniques, materials chemistry and biology with engineering, and the application of basic science. In fact, the last few decades of research have led to the emergence of numerous material options, along with an increasing sophistication in the ability to tune and manipulate complex physical, biological, and mechanical properties. Moreover, some of these materials have already entered clinical practice, and others will certainly be entering practice shortly. Since the field is still expanding at an accelerated pace, here we aim to collect the latest advances by including materials with improved structural, mechanical, and architectures features as well as the state-of-the-art of all aspects associated with the technologies used for their biofabrication for future applications in biomedical engineering and regenerative medicine. The purpose of this Special Issue is to collate investigators who have been working in this field, whether from a theoretical, experimental, or engineering perspective, in order to develop a sense of what has been accomplished so far, and how much remains to be explored. Original works are welcome as well as reviews of the field.

Dr. Raffaele Pugliese
Guest Editor

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