Precision Medicine for Chronic Diseases

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 2841

Special Issue Editors


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Medical Pathology, Nutrition and Clinical Exercise Group (PaMNEC) of Multidisciplinary Research, Center of Egas Moniz (CiiEM), Escola Superior de Saúde Egas Moniz, 2829-511 Caparica, Portugal
Interests: nursing; personalized medicine; physical rehabilitation; neurorehabilitation; qualitative research; health promotion
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Medical Pathology, Nutrition and Clinical Exercise Group (PaMNEC), Multidisciplinary Research Center of Egas Moniz (CiiEM), 2829-511 Caparica, Portugal
Interests: neurological diseases; Parkinson's disease; elderly and aging; clinical exercise; non-pharmacologic interventions
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
i3S - Institute for Research and Innovation in Health, University of Porto, Porto, Portugal
Interests: regenerative medicine; mesenchymal stem cells; stem cells secretome; bioreactor cell culture; exosomes; astrocyte reactivity; neuron-glia communication; 3D culture systems; Parkinson's disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Living with a chronic condition can be stressful because it changes patients’ lives, distressing their physical and/or mental health or threatening their survival. Nevertheless, people are able to take steps to cope with these new situations, manage their condition, and maintain a good quality of life. These patients have different disease statuses and management requirements, and so providing optimal care is key. Precision health considers genetic and genomic sequence, protein, metabolite, and microbiome information—collectively known as “omics”—with lifestyle, social, economic, cultural, and environmental factors. Combining these high-tech and high-touch approaches allows healthcare professionals to formulate treatment and prevention strategies based on patients’ unique backgrounds and conditions. Precision health can improve aspects of physical health, mental health, and the ability to self-manage conditions. This new approach represents a fundamental shift to more proactive and personalized care that empowers people with chronic conditions to lead healthy lives. With this Special Issue, we aim to publish articles describing precision health approaches to the diagnosis and treatment of chronically ill patients.

We encourage the submission of manuscripts that look at precision health and contribute to the development of knowledge in this field. Potential topics include, but are not limited to: ensuring access to precision health for people with chronic conditions; pathways for precision health; protecting and supporting people with chronic conditions through precision health; benefits of the precision health approach; challenges to the delivery of precision health for people with chronic conditions.

Dr. Júlio Belo Fernandes
Dr. Catarina Godinho
Dr. Fábio G. Teixeira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • precision health
  • personalized care
  • person-centredness
  • patient participation
  • empowerment
  • chronic conditions
  • chronic disease

Published Papers (1 paper)

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Review

19 pages, 1156 KiB  
Review
Current Trends and Challenges of Fecal Microbiota Transplantation—An Easy Method That Works for All?
by Cátia Almeida, Rita Oliveira, Pilar Baylina, Rúben Fernandes, Fábio G. Teixeira and Pedro Barata
Biomedicines 2022, 10(11), 2742; https://doi.org/10.3390/biomedicines10112742 - 28 Oct 2022
Cited by 8 | Viewed by 2423
Abstract
The gut microbiota refers to bacteria lodges in the gastrointestinal tract (GIT) that interact through various complex mechanisms. The disturbance of this ecosystem has been correlated with several diseases, such as neurologic, respiratory, cardiovascular, and metabolic diseases and cancer. Therefore, the modulation of [...] Read more.
The gut microbiota refers to bacteria lodges in the gastrointestinal tract (GIT) that interact through various complex mechanisms. The disturbance of this ecosystem has been correlated with several diseases, such as neurologic, respiratory, cardiovascular, and metabolic diseases and cancer. Therefore, the modulation of the gut microbiota has emerged as a potential therapeutic tool; of the various forms of gut microbiota modulation, fecal microbiota transplantation (FMT) is the most approached. This recent technique involves introducing fecal material from a healthy donor into the patient’s gastrointestinal tract, aiming to restore the gut microbiota and lead to the resolution of symptoms. This procedure implies a careful donor choice, fine collection and handling of fecal material, and a balanced preparation of the recipient and consequent administration of the prepared content. Although FMT is considered a biological therapy with promising effects, side effects such as diarrhea and abdominal pain have also been claimed, making this a significant challenge in the application of FMT. Bearing this in mind, the present review aims to summarize the recent advances in understanding FMT mechanisms, their impact across different pathological conditions, and the associated side effects, emphasizing the most recent published data. Full article
(This article belongs to the Special Issue Precision Medicine for Chronic Diseases)
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