Special Issue "Advances in Fatty Acid Metabolism as the Markers of Civilization Diseases 2.0"
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".
Deadline for manuscript submissions: 31 December 2023 | Viewed by 1003
Special Issue Editor
Interests: fatty acids metabolism; inflammatory process; eicosanoids; SCFA; PUFA; MUFA; nutriepigenomics; chromatography; ischemic stroke; NAFLD; NASH
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Fatty acids (FA), as the basic component of cell membranes, participate in maintaining the homeostasis of cellular metabolism, cell signaling and gene expression. Fatty acids are a biochemically diverse group of organic compounds in terms of their structure and origin. Regulatory functions in humans body are performed by both SCFA short-chain fatty acids, produced by the bacteria from gut microbiome, and dietary fatty acids, mainly PUFA n3 and n6. The FA are very important factors modifying a number of metabolic pathways in our body, and at the same time being their components. Eicosanoids, EPA and DHA derivatives, such as prostaglandins, leukotrienes, resolvins, protectins and maresins, are anti-inflammatory or pro-inflammatory mediators. Low-intensity inflammation may be associated with susceptibility to developing non-communicable chronic diseases (NCCD), such as obesity, lipid disorders and NAFLD, cardiovascular diseases (CVD), type 2 diabetes (T2D), insulin resistance , or some types of cancers. It is also believed that disturbance of lipid homeostasis is also associated with neurological disorders as well as neurodegenerative diseases such as Alzheimer's disease (AD).
I have hope that the recent advances in lipidometabolomics help a better understanding of the role of some nutritional factors, including fatty acids, in the development of civilization diseases. It is possible that understanding the fatty acid profile in these diseases will allow for the development of new diagnostic, therapeutic, and prophylactic strategies. I invite scientists to share their experiences in this area in the form of original research and review articles.
Dr. Arleta Drozd
Guest Editor
Manuscript Submission Information
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Keywords
- fatty acids
- lipidomics
- biochemistry
- infalmmation
- pathophysiological mechanisms
- lipid mediators
- gut microbiota
- NAFLD/NASH
- insulin resistance
- type 2 diabetes
- endocine diseases
- cardiovascular diseases
