Dentistry, Orthodontics and Maxillo-Facial Surgery, Traditional and Smart Approaches

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: closed (20 August 2023) | Viewed by 4331

Special Issue Editor

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Guest Editor
Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70124 Bari, Italy
Interests: orthodontics; pediatric dentistry; oral medicine; oropharyngeal neoplasms; hygiene; prevention
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Dental and craniofacial diseases are a common term for an extensive group of diseases with multiple characteristics and a variety of craniofacial manifestations. Moreover, systemic conditions such as cardiovascular disease (CVD), adverse pregnancy outcomes and unbalanced functional occlusion could critically impact the general well-being of both growing and adult patients. In elderly patients, the good maintenance of oral health, which manifests as an efficient mastication and a mouth free of inflammation, is a part of the WHO recommendations for healthy aging. The oral commensal could become pathogenic upon migration to extra-oral sites and the direct or indirect toxic effects of viruses, fungi and bacteria and their products, and can maintain a status of general chronic inflammation that is a common environment for many diseases. Non-invasive diagnosis of numerous systemic illnesses is possible through testing saliva, for its intrinsic availability and easy collection; this has increased interest in the oral microbiome, oral cavity biology and biomechanics. To determine the significance of this initial evidence, integrated with the more traditional field of medical imaging and recently developed machine learning techniques, a sub-area of artificial intelligence, can greatly contribute to the concept of the mouth as window of human well-being. The aim of this Special Issue is to collect methods, pilot studies and feasibility research and evidence-based data on the mouth and the use of diagnostic and therapeutic instruments for oral cavities for the wellness of the entire body, as the principle “earlier the diagnosis is made, sooner treatment can begin, and better will be the outlook of patients” is applicable here.

Dr. Assunta Patano
Guest Editor

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  • dental
  • dentistry
  • maxillofacial
  • images
  • saliva
  • biomarkers
  • orthodontics
  • aligners
  • artificial intelligence
  • sensors

Published Papers (1 paper)

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37 pages, 4988 KiB  
Systematic Review
MRONJ Treatment Strategies: A Systematic Review and Two Case Reports
by Angelo Michele Inchingolo, Giuseppina Malcangi, Irene Ferrara, Assunta Patano, Fabio Viapiano, Anna Netti, Daniela Azzollini, Anna Maria Ciocia, Elisabetta de Ruvo, Merigrazia Campanelli, Pasquale Avantario, Antonio Mancini, Francesco Inchingolo, Ciro Gargiulo Isacco, Alberto Corriero, Alessio Danilo Inchingolo and Gianna Dipalma
Appl. Sci. 2023, 13(7), 4370; - 29 Mar 2023
Cited by 6 | Viewed by 4011
MRONJ is a serious drug-related side effect that is most common in people using antiresorptive and/or angiogenic medications. Therapy options for this condition include conservative treatments, surgical procedures with varied degrees of invasiveness, and adjuvant therapies. The aim of the present study is [...] Read more.
MRONJ is a serious drug-related side effect that is most common in people using antiresorptive and/or angiogenic medications. Therapy options for this condition include conservative treatments, surgical procedures with varied degrees of invasiveness, and adjuvant therapies. The aim of the present study is to identify the most successful and promising therapy alternatives available to clinicians. PubMed, Cochrane, Scopus, Web of Science, and Embase were searched for works on our topic published between 8 January 2006 and 8 January 2023. The search was restricted to randomized clinical trials, retrospective studies, clinical studies, and case series involving human subjects with at least five cases and no age restriction on participants. A total of 2657 was found. After the selection process, the review included 32 publications for qualitative analysis. Although conservative treatments (pharmacological, laser, and minimally invasive surgery) are effective in the early stages of MRONJs or as a supplement to traditional surgical resection therapy, most studies emphasize the importance of surgical treatment for the resolution or downstaging of advanced lesions. Fluorescence-guided surgery, PRP, PRF, CGF, piezosurgery, VEGF, hyaluronic acid, and ozone therapy all show significant potential for improving treatment outcomes. Full article
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