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Nutrients
Volume 14
Issue 14
10.3390/nu14142922
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Article
Peer-Review Record

Status and Dietary Intake of Phytoene and Phytofluene in Spanish Adults and the Effect of a Four-Week Dietary Intervention with Lutein-Rich Fruits or Vegetables

Nutrients 2022, 14(14), 2922; https://doi.org/10.3390/nu14142922
by Elena Rodríguez-Rodríguez 1,*, Rocío Estévez-Santiago 2, Milagros Sánchez-Prieto 3 and Begoña Olmedilla-Alonso 3,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Nutrients 2022, 14(14), 2922; https://doi.org/10.3390/nu14142922
Submission received: 10 June 2022 / Revised: 6 July 2022 / Accepted: 15 July 2022 / Published: 17 July 2022
(This article belongs to the Special Issue Carotenoid Biomarkers of Dietary Exposure and Nutritional Status)

Round 1

Reviewer 1 Report

This manuscript explains the analysis of phytoene and phytofluene carotenoid content in spanish adults after dietary  intervention. 

Minor comments,

Few typos 

1st page - "activite"

5th page - "shoes"

6th page - "though"

7th page - "carrt" 

why do you expect lutein will have a effect on PT and PTF, because it can cleave by mammalian carotenoid oxygenases? but PT and PTF are not a product of these CCDs.

 

Author Response

Response to Reviewer 1 Comments

Point 1. Few typos

Response: Typing errors in those lines have been corrected and, we have corrected others throughout the manuscript.

Point 2. why do you expect lutein will have a effect on PT and PTF, because it can cleave by mammalian carotenoid oxygenases? but PT and PTF are not a product of these CCDs.

Response: The present study included data and samples from participants in a couple of previous studies (observational and intervention). Thus, this study was performed in 101 participants enrolled in a previous observational study to assess lutein and zeaxanthin dietary and status markers. In a next step, from this group we established two subgroups and those volunteers (n=29) participated in a four-week dietary intervention study with fruit or vegetable rich in lutein.

Answering your question, we did not expect an effect of lutein intake on PT and PTF nutritional status markers. We aimed to contribute with data on PT and PTF in several status markers and in the dietary intake in healthy adults because there is very little data on these carotenoids that are biologically active.

Reviewer 2 Report

All the figures of this manuscript are missing. Please provide them and resubmit.

Author Response

Response to Reviewer 2 Comments

Point 1. All the figures of this manuscript are missing. Please provide them and resubmit.

Response: Although the figures were included in the manuscript submitted to Nutrients (in the file with the Nutrients template), we saw they are not in the present file. Now, we have uploaded them (1 word file).

 

Author Response File: Author Response.docx

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