Progress and Applications of Reverse Genetics in Virology
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".
Deadline for manuscript submissions: 15 June 2024 | Viewed by 1595
Special Issue Editor
Interests: investigating the genetic evolution of important human pathogenic viruses; the pathogenesis of severe viral diseases and the molecular mechanisms of viral infection and transmission; developing novel viral tools and antiviral strategies
Special Issue Information
Dear Colleagues,
Reverse genetics, diverging from traditional forward genetics, has reshaped our understanding of genotype–phenotype relationships. By directly altering genetic sequences to achieve a desired phenotype, it surpasses the standard approach based on genetic variance. Modern molecular techniques and genome sequencing have expanded the reach and applicability of reverse genetics.
Viruses, due to their simplified genomic structures, serve as prime subjects for reverse genetics. Their readily modifiable genomes have led to significant advancements in viral biology, unearthing gene functions, optimizing microbiological resources, reviving rare viral strains, and aiding in vaccine development.
For this Special Issue, "Progress and Applications of Reverse Genetics in Virology", we invite the submission of original research and review articles focused on new technologies and novel approaches for the implications of reverse genetics, including (but not limited to) dsDNA virus, ssDNA virus, dsRNA virus, +ssRNA virus, -ssRNA virus, Ambisense RNA virus, etc.
Dr. Yang Liu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- reverse genetics
- virus infectious clone
- virus rescue
- modified cell line for viral amplification
- viral vector tools
- reporter viruses
- trans-complementary system
- pseudovirus
- chimeric virus
- virus replicon
- virus minigenome system
- replication-deficient viruses
- viral genetic evolution
