Bioinformatics-Driven Analysis of Mechanisms Underlying the Function and Evolution of Pandemic Viruses
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 13192
Special Issue Editors
Interests: pandemic viruses; vaccines; synthetic biology and biotechnology; motif identification; protein engineering; biocatalysis; bioremediation; neurodevelopment and neurological disorders; biomimetics and regenerative medicine; subcellular trafficking
Special Issues, Collections and Topics in MDPI journals
Interests: pandemic viruses; vaccines; structural predictions and simulations; enzyme evolution and engineering; biocatalysis; design of biomimetic molecules
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent decades, progress in molecular sciences and bioinformatics has strongly enhanced discoveries in every field of life sciences, including virology. At the same time, the power of computational biology has improved the rational design of antivirals through high-confidence simulations.
This Special Issue aims to report bioinformatics-driven analyses of pandemic viruses, such as influenza A virus and coronaviruses, that are able to:
- Shed light on trends in virus clade/subclade/variant evolution;
- Identify or suggest sequence/structural fingerprints in virus–host interactions, and eventually identify underlying host specificity and host jump (zoonosis) phenomena;
- Identify or suggest crucial mutations resulting in epitope variation, and hence, “immune escape”;
- Identify sequence/structural motifs (and their variation) modulating the binding affinity to functional receptors of the host, thus predicting tissue-specific spreading and pathogenicity;
- Guide and/or improve the design of antiviral molecules and vaccines.
Dr. Francesco Filippini
Dr. Irene Righetto
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pandemic virus
- avian influenza
- coronavirus
- SARS-CoV-2
- immune escape
- structural bioinformatics
- variant
- mutation
- antiviral design
- host jump
- pathogenicity shift
- antiviral design
- epitope identification
