Novel Perspectives in Virucidal Disinfection

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1221

Special Issue Editors


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Guest Editor
Laboratory Prof. Gisela Enders MVZ GbR, 70193 Stuttgart, Germany
Interests: antiviral activity; efficacy of disinfectants

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Guest Editor
Institute of Hygiene and Environmental Medicine, Ernst Moritz Arndt University, Walther-Rathenau-Str. 49a, 17489 Greifswald, Germany
Interests: antimicrobial agents; antibiotic; antiviral; disinfectants

Special Issue Information

Dear Colleagues,

Preventing the development of an infection is a core principle of medical treatment and public health. One of the main tools that are employed to achieve this goal is hygiene and disinfection measures. In addition to bacterial and fungal pathogens, the presence of pathogenic viruses must always be expected, especially in medical and care facilities. Therefore, the availability of virucidal disinfection is crucial. However, the number of virucidal agents is quite limited and their mode of action has not always been fully understood. In addition to known active ingredients, additions as well as alternatives are urgently needed. For instance, the development of active components that are produced sustainably as well as new approaches containing antimicrobial active ingredients for surfaces are essential. Moreover, as with all biocides, virucidal products should not only be active but also safe to use.

However, not only agents and applications but also novel methods for testing the efficacy and safety of agents and products are needed to ensure further development of virucidal disinfection. Moreover, a better understanding of viral disinfection mechanisms at the molecular level is fundamental to this process.  

Therefore, in this Special Issue, we invite our colleagues to submit original scientific reviews and research articles highlighting advances in our understanding and development of all aspects of viral disinfection, including (but not limited to): (1) approaches to disinfection; (2) active ingredients; (3) methods for efficacy and safety testing; (4) surrogate viruses for efficacy testing; (5) spectrum of virucidal activity; and (6) understanding the molecular mechanisms of virucidal disinfection, including their possible resistance occurrence.

Dr. Maren Eggers
Prof. Dr. Nils-Olaf Hübner
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • approaches to disinfection
  • active ingredients
  • surrogate viruses for efficacy testing
  • spectrum of virucidal activity
  • molecular mechanisms
  • virucidal disinfection

Published Papers (1 paper)

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Research

13 pages, 2934 KiB  
Article
UV-C Light Intervention as a Barrier against Airborne Transmission of SARS-CoV-2
by Izabela Ragan, Jessie Perez, Wilson Davenport, Lindsay Hartson and Branden Doyle
Viruses 2024, 16(1), 89; https://doi.org/10.3390/v16010089 - 05 Jan 2024
Viewed by 1060
Abstract
Background: SARS-CoV-2 continues to impact human health globally, with airborne transmission being a significant mode of transmission. In addition to tools like vaccination and testing, countermeasures that reduce viral spread in indoor settings are critical. This study aims to assess the efficacy of [...] Read more.
Background: SARS-CoV-2 continues to impact human health globally, with airborne transmission being a significant mode of transmission. In addition to tools like vaccination and testing, countermeasures that reduce viral spread in indoor settings are critical. This study aims to assess the efficacy of UV-C light, utilizing the Violett sterilization device, as a countermeasure against airborne transmission of SARS-CoV-2 in the highly susceptible Golden Syrian hamster model. Methods: Two cohorts of naïve hamsters were subjected to airborne transmission from experimentally infected hamsters; one cohort was exposed to air treated with UV-C sterilization, while the other cohort was exposed to untreated air. Results: Treatment of air with UV-C light prevented the airborne transmission of SARS-CoV-2 from the experimentally exposed hamster to naïve hamsters. Notably, this protection was sustained over a multi-day exposure period during peak viral shedding by hamsters. Conclusions: These findings demonstrate the efficacy of the UV-C light to mitigate against airborne SARS-CoV-2 transmission. As variants continue to emerge, UV-C light holds promise as a tool for reducing infections in diverse indoor settings, ranging from healthcare facilities to households. This study reinforces the urgency of implementing innovative methods to reduce airborne disease transmission and safeguard public health against emerging biological threats. Full article
(This article belongs to the Special Issue Novel Perspectives in Virucidal Disinfection)
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